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作 者:许翠萍[1,2] 韩春荣[1,2] 耿引凤[1,2]
机构地区:[1]山西医科大学第一临床医学院消化科 [2]轩岗矿务局医院内科
出 处:《山西医科大学学报》1998年第4期303-304,共2页Journal of Shanxi Medical University
摘 要:为探讨肥大细胞在慢性肝病中的作用,应用甲苯胺蓝染色和免疫组化染色观察50例人肝组织中肥大细胞与储脂细胞的密度和分布特征。结果显示慢性肝病组肥大细胞与储脂细胞密度都有增加,各自与正常肝组织相应指标比较差异有显著性(P<005),且二者在数量的增加程度方面呈正相关(γ=082),分布以结缔组织区域多见。Objective: To study the function of mast cells in chronic liver diseases Method: The density and characteristic of distribution of the mast cells and fat storing cells in tissue specimens of human liver tissue from 50 normal subjects and cases of chronic liver diseases were observed by using toluidine blue staining and immunohistochemical staining Results: The density of mast cells and fat storing cells in diseased liver tissue was significantlly higher than that in normal liver tissue (P<0 05),the increases in number of mast cells and fat-storing cells were of posittive correlation(r=0 82),and the distributions of them were richer in the region of connective tissue Conclusion: Mast cells may play an important role in the pathogenesis of chronic liver disease
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