血清总唾液酸和癌胚抗原联合检测对结直肠癌的诊断价值  

Serum Total Sialic Acid and Carcinoembryonic Antigen Combined Detection of Colorectal Cancer Diagnosis

作　　者：苏咏梅[1] 杨洪亮[1] 

机构地区：[1]牡丹江医学院附属二院检验科,牡丹江157011

出　　处：《中国医药导刊》2009年第10期1750-1751,共2页Chinese Journal of Medicinal Guide

摘　　要：目的:探讨血清总唾液酸(TSA)和癌胚抗原(CEA)联合检测对结直肠癌患者的诊断价值。方法:分别采用改良苯二酚法和放射免疫法测定结直肠癌患者血清的总唾液酸(TSA)和癌胚抗原(CEA)的值,并与正常体检的健康人群进行对照。结果:总唾液酸(TSA)、癌胚抗原(CEA)在肠癌患者中的检出率分别是59.2%、54.2%,明显高于正常对照组(P<0.01),二者联合检测的总检出率为70.2%,高于各单项检测(P<0.01)。结论:血清总唾液酸(TSA)和癌胚抗原(CEA)的联合检测提高了结直肠癌诊断的敏感性。Objective： To investigate serum total sialic acid （TSA） and carcinoembryonic antigen （CEA） combined detection of colorectat cancer diagnosis. Methods： The modified hydroquinone were used method and measured by radioimmunoassay in patients with colorectal cancer serum total sialic acid （TSA） and carcinoernbryonic antigen （CEA） value, and with a normal physical examination of healthy people as control. Results： The total sialic acid （TSA）, carcinoembryonic antigen （CEA） in patientS with eoloreetal caucer detection rate was 59.20,54.2%, significantly higher than the normal control group （P〈0.01）, both the total joint detection The detection rate was 70.2%, higher than the individual test （P〈0.01）. Conclusion： The serum total sialic acid （TSA） and carcinoembryonic antigen （CEA） to improve end to the joint detection of the sensitivity of cancer diagnosis has important clinical value.

关 键 词：血清总唾液酸 癌胚抗原 结直肠癌 

分 类 号：R735.3[医药卫生—肿瘤]