氢质子磁共振波谱鉴别脑膜瘤术后反应性损伤残留与复发  

The role of 1H-MRS to differentiate residual or recurrent Meningioma from non-neoplastic lesions

作　　者：丛也彤[1] 亓波[1] 

机构地区：[1]吉化总医院CT科,吉林吉林市132021

出　　处：《中国实验诊断学》2009年第10期1410-1412,共3页Chinese Journal of Laboratory Diagnosis

摘　　要：目的探讨脑膜瘤术后的1H-MRS表现及其临床意义。方法收集32例脑膜瘤病例于术后7天、30天、3个月行增强MRI和1H-MRS检查。使用西门子novus1.5T超导磁共振成像仪分析各种代谢物的变化。结果在术后反应性强化组中各代谢物与正常组织相比均无明显差异(P>0.05)。在残留和复发的脑膜瘤中各种代谢物术后不同时间、不同区域与正常组织相比有显著性差异(P<0.05)。结论1H-MRS与增强MRI结合能更好的提高脑膜瘤术后反应性损伤与残留及复发鉴别诊断的准确性。Objective To evaluate the role of 1H-MRS in the diagnosis of differentiate residual or recurrent Meningioma from non-neoplastic lesions.Methods Collected thrity-two patients with meningioma,All the patients were received enhanced MRI and 1H-MRS respectively on the 7 th,30 th day and 3 rd month after the operation.Multivoxel proton MRS was performed on Toshiba ExcelARTTM1.5T and diversified metabolite peaks were measured among different time and regions.Results Compared with normal,the metabolic ratios of reactive enhanced region showed no significantly diffrence in different region and time.NAA/Cho、NAA/Cr,、Cho/Cr、Ala、Glu、Lip and Lac showed significant difference in different region and time after the operation in residual/recurrent meningioma（P〈0.05）.Conclusion 1H-MRS combined with enhanced MRI can improve diagnostic accuracy of differentiating residual/recurrent meningioma from non-neoplastic lesions.

关 键 词：脑膜瘤切除术 磁共振波谱 磁共振成像 代谢 

分 类 号：R739.45[医药卫生—肿瘤]