前部缺血性视神经病变图形视觉诱发电位分析  

The Analysis of Pattern-Reversal Visual Evoked Potential with Anterior Ischemic Optic Neuritis

作　　者：邸悦[1] 王智[1] 周晓东[1] 

机构地区：[1]复旦大学附属金山医院眼科,上海200540

出　　处：《中国临床医学》2009年第5期800-801,共2页Chinese Journal of Clinical Medicine

摘　　要：目的:分析图形视觉诱发电位(PVEP)的潜伏期(LP100)及振幅(AP100)对前部缺血性视神经病变(AION)视神经传导异常的诊断价值。方法:对临床证实为AION的48例单眼发病的患者行PVEP检查,对LP100及AP100诊断AION的敏感度及特异度进行对比分析。结果:LP100延长诊断AION视神经传导异常的敏感度及特异度分别为58.3%及95.8%,AP100降低诊断AION视神经传导异常的的敏感度及特异度分别为85.4%及89.6%;如果综合LP100AP100这两项指标,以两项指标中任意一项阳性即诊断AION存在视神经传导异常,可获得97.9%的敏感度及87.5%的特异度。结论:PVEP在诊断AION视神经传导异常中有重要价值,综合潜伏期及振幅这两项指标可以明显提高诊断效率。Objective： To evaluate the clinical effect on amplitude and latency of pattern reversal visual evoked potential （PVEP） in patients with anterior ischemic optic neuritis. Methods： Forty-eight ischemic optic neuritis patients were selected. The diagnostic efficiency of amplitude and latency of pattern revereal visual evoked potentiall were evaluated. Results： The sensitivity of LP100 in diagnosing ischemie optic neuritis was 58.3% and the specificity was 95.8% in nerve conduction abnormal. The sensitivity of AP%, in diagnosing ischemic optic neuritis was 85.4% and the specificity was 89.6% in nerve conduction abnormal. By using either LP100, or AP100 a sensitivity of 97.9% and a specificity of 87.5% could be achieved. Conclusion：PVEP is effective in the diagnosis of ischemie optic neuritis. The diagnosis efficiency could be elevated considering both of latency and amplitude.

关 键 词：图形视觉诱发电位 前部缺血性视神经病变 潜伏期 振幅 

分 类 号：R774.6[医药卫生—眼科]