液囊空肠管在胃癌术后早期肠内营养支持的临床研究  

Clinical study on early enteral nutrition in postoperative patients with gastric cancer through liquid capsule jejunal tube

作　　者：钟漓[1] 张广钰[1] 董陈诚[1] 卢崇亮[1] 

机构地区：[1]桂林医学院附属医院普通外科,广西桂林541001

出　　处：《华夏医学》2009年第5期817-819,共3页Acta Medicinae Sinica

摘　　要：目的:研究使用液囊空肠管在胃癌术后早期肠内营养支持治疗的安全性、可行性及临床作用。方法:选择胃癌根治性手术86例患者,随机分为肠内营养(EN)46例,肠外营养(PN)40例。EN组通过液囊空肠管术后24h开始肠内营养,PN组给予静脉营养。检测手术前后营养状况、免疫指标及观察临床表现。结果:术后EN组血清前蛋白、转铁蛋白、IgA、IgG、IgM及CD3、CD4/CD8较PN组上升快,差异有统计学意义(P<0.05);肛门排气时间EN组比PN组早(P<0.05);术后住院时间EN组较PN组短(P<0.05);并发症及营养治疗费用EN组较PN组少(P<0.01)。结论:胃癌术后给予早期肠内营养支持,可促进胃肠功能恢复、改善营养代谢、减少并发症的发生、缩短术后住院日、减轻营养治疗费用,液囊空肠管应用有安全、无并发症及便于护理优点。Objective： To investigate the safety, feasibility and clinical effects of early enteral nutrition （EN）in postoperative patients with gastric cancer through liquid capsule jejunal tube. Methods：86 cases patients with gastric cancer were randomly divided into enteral （EN ,n= 46）, parenteral （PN,n= 40）groups postoperatively. The EN group was treated with EN after 24h postoperatively, and the PN group received normal TPN. The nutritional and immune parameters and clinical findings were observed. Results ：The restoring time of prealbumin and transferin in serum in EN group was shorted as compared with PN group. There was statistical significance between EN and PN groups （P〈0.05）. The level of IgA,IgG,IgM and CD3,CD4/CD8 in EN group rised more swiftly than PN group. The difference was statistical significant （P〈0. 05）. Recovery time of intestinal function was earlier in EN group than that in PN group（P〈0. 05）. The mean postoperative hospital stay of the EN group was significantly shorter than that of the EN group. The complications were less and treatment fee was significantly lower than that in PN group. Conclusion： Using nutrition multifibre for early enteral nutrition through liquid capsule jejunal tube is safe and effective after gastric operation. It can promote gastrointestinal function recovery and improve nutritional metabolism.

关 键 词：胃癌术后 肠内营养 早期 液囊空肠管 

分 类 号：R735.2[医药卫生—肿瘤]