度洛西汀治疗广泛性焦虑症的对照研究  

A study of duloxetine in the treatment of general anxiety disorder

作　　者：陈巧平[1] 

机构地区：[1]广东省佛山市顺德区第一人民医院心理科,528300

出　　处：《中国临床实用医学》2009年第11期59-60,共2页China Clinical Practical Medicine

摘　　要：目的探讨度洛西汀对广泛性焦虑症的治疗效果及药物的不良反应。方法对52例诊断为广泛性焦虑症的患者，随机分为治疗组（27例）和对照组（25例），治疗组给予度洛西汀，对照组给予阿米替林，治疗6周。在治疗前后分别给予汉密尔顿焦虑量表（HAMA）、临床疗效总评量表（CGI）和副反应量表（TESS）评定疗效和不良反应。结果两种药物的疗效相仿。度洛西汀不良反应少而轻。结论度洛西汀是治疗广泛性焦虑症安全有效的药物。Objective To study the efficacy and side effects of duloxetine in treatment of general anxiety disorder. Methods 52 patients were randomly assigned to therapeutic group（n = 27）and control group（n = 25 ） for 6 weeks. Therapeutic group were given duloxetine and control group were given amitriptyline. The clinical effect was assessed with HAMA,CGI and side effects were assessed by TESS. Results Both drugs showed similar efficacy in the treatment of general anxiety disorder. Duloxetine had less and slighter side effects. Conclusion Duloxetine is a safe and efficient drug in the treatment of general anxiety disorder.

关 键 词：广泛性焦虑 度洛西汀 阿米替林 

分 类 号：R749.4[医药卫生—神经病学与精神病学]