对甲氧基苯基丙酮的合成  

The synthesis of p-methoxyphenylacetone

作　　者：张翠娥[1] 刘敏[1] 韩建[1] 

机构地区：[1]西安近代化学研究所,陕西西安710065

出　　处：《应用化工》2009年第10期1540-1541,1544,共3页Applied Chemical Industry

摘　　要：报道了对甲氧基苯基丙酮的合成方法。由对甲氧基苯甲醛和2-氯丙酸甲酯为原料,经环合、水解和亚硫酸氢钠处理,再进行减压蒸馏获得目标产物。合成总收率80%以上,产品纯度达98%以上。A synthetic method for p-methoxyphenylacetone from p-methoxybenzaldehyde and methyl 2-chloropropionate was described. Target compound was prepared through cyclicondensation,hydrolysis, treatment with sodium bissulfite and distillation at reduced pressure,with the yield over 80% and purity over 98%.

关 键 词：对甲氧基苯甲醛 对甲氧基苯基丙酮 合成 

分 类 号：R743[医药卫生—神经病学与精神病学]