单氟磷酸钠加入可摘局部义齿热凝基托树脂后氟离子的体外释放实验  

An in vitro study of fluoride release rate of F-containing thermoplastic resina

作　　者：郭菁[1] 朱洪水[1] 

机构地区：[1]南昌大学口腔医学院,330006

出　　处：《实用口腔医学杂志》2009年第5期638-641,共4页Journal of Practical Stomatology

摘　　要：目的:通过观测加单氟磷酸钠热凝基托树脂的氟释放率,寻找一种较为理想的给氟剂量预防义齿基牙龋。方法:将含单氟磷酸钠0、10%、15%、20%、25%(单氟磷酸钠占牙托粉的重量比)5种不同浓度的热凝树脂各3块,每块重1 g,分别随机放入装有100、200、500 ml蒸馏水的聚乙烯盒中浸泡,前2种溶液定期完全更换浸泡用的蒸馏水(第1、2、3、6、9、16天换水,以后为每7 d换水,共2个月),每次留取2 ml浸泡液待测。500 ml溶液定期取浸泡液2 ml,取液期间不换水,第3、6、9天取液1次,以后每7 d取液1次,待测,共2个月。用氟离子选择电极法测量待测溶液中氟离子浓度,观察和对比树脂中氟的释放速率及释放规律。结果:各浓度含氟树脂块在观察期间于浸泡液中均能释放不同浓度氟离子。结论:将单氟磷酸钠加入热凝基托树脂中,具有良好的缓释氟的作用;15%的单氟磷酸钠是较好的加氟比例。Objective：To observe the fluoride release rate of F-containing thermoplastic resina,trying to find a suitable concentration of fluoride in thermoplastic resina to prevent caries in base teeth of partial denture restorations.Methods：Na2（PO3）F-containing thermoplastic resina,respectively 0,10%,15%,20% and 25%（w/w）in concentration were cut into three 1 g blocks and immersed in 100,200 and 500 ml deionized water.These composite resins in 100 ml and 200 ml solutions were replaced every 1,2,3,6,9,16 days（every 7 days after that）until two months later,500 ml solution was reserved after 3,6,9 days every 7 days later until two months,2 ml of which were reserved every time.The fluoride release rates of these thermoplastic resina were tested by potentiometry.Results：All thermoplastic resina containing different concentrations of fluoride could release F-during the period of 65 days.Conclusion：When Na2（PO3）F is mixed in thermoplastic resina,it releases fluoride slowly.Thermoplastic resina containing 15% F-has higher release rates of fluoride.

关 键 词：基托加氟 缓释氟 释放率 龋齿 

分 类 号：R783.1[医药卫生—口腔医学]