CD44v6在腮腺多形性腺瘤中的表达  

A study of CD44v6 expression in parotid pleomorphic adenomas

作　　者：宋具昆[1] 黄光磊[1] 赵科[1] 许平[1] 陈昊[1] 罗洪[1] 

机构地区：[1]贵州省人民医院口腔科,550002

出　　处：《实用口腔医学杂志》2009年第5期744-745,共2页Journal of Practical Stomatology

摘　　要：初步研究CD44v6在腮腺多形性腺瘤中的表达情况及其与肿瘤复发的关系。采用免疫组织化学SP法对初次手术后复发,又再次入院行复发灶切除术的多形性腺瘤病例10例2次术后石蜡标本及10例正常腮腺组织石蜡标本进行CD44v6检测,分析其与腮腺多形性腺瘤复发关系。结果表明CD44v6在肿瘤组织中的表达高于正常腮腺组织,在复发多形性腺瘤中呈现低表达。CD44v6的表达变异可能与腮腺多形性腺瘤的复发有关。To explore the relationship of the expression of CD44v6 with tumor recurrence in parotid pleomorphic adenoma and its clinical significances,SP immunohistochemical staining was employed in the 10 cases of CPA and 10 cases of PA,10 cases of normal parotids.The relationship of the expression of CD44v6 with tumor recurrence in parotid pleomorphic adenoma was studied.The positive rate of expression of CD44v6 in CPA was much lower than that in PA tissues,the positive rate of expression of CD44v6 in CPA and PA was significantly higher than that in normal parotid tissues.The expression of CD44v6 in CPA tissues was lower than that in PA tissues and may be correlated with tumor recurrence.

关 键 词：CD44V6 腮腺多形性腺瘤 SP免疫组织化学 

分 类 号：R739.8[医药卫生—肿瘤]