周期性眼外负压吸引对角膜地形的影响  

The effects of periodical vacuum-suction on corneal topography

作　　者：李珊珊[1,2] 戴锦晖[1] 周行涛[1] 

机构地区：[1]复旦大学附属眼耳鼻喉科医院眼科,上海硕士研究生200031 [2]上海市眼病防治中心,200040

出　　处：《眼科研究》2009年第10期889-892,共4页Chinese Ophthalmic Research

摘　　要：目的探讨周期性眼外负压吸引对角膜地形的影响及可能原因。方法随机选取"球外反博"治疗患者40例(40眼),以眼外负压100 mmHg/3 s速度升高至(300±20)mmHg,维持5 s后释放负压至0,间隔1 min重复,共10个循环。试验后1、5、15 min检测患者角膜地形图、视力、眼压、眼表状况、自觉症状等。以受试眼自身前后对照,分析角膜不规则指数(CIM)、形状因子(SF)、角膜散光度(ASTIG)等角膜地形指标。结果周期性眼外负压吸引后随时间的变化,ASTIG、CIM变化差异均有统计学意义(F=7.62,P=0.006;F=0.431,P=0.001),吸引后15 min恢复至吸引前状态;SF的改变差异无统计学意义(F=0.635,P=0.050 2)。性别、眼别及瞳孔大小差异均无统计学意义(P>0.05)。吸引结束后,轻度眼部不适4例(10%),结膜轻度充血15例(37.5%),有轻度角膜上皮点状脱失1例(2.5%),轻度视物模糊2例(5%)。吸引结束后15 min,患者视力均无下降,眼压在正常范围内。结论周期性眼外负压吸引对角膜表面形状有一定影响,随着时间的推移该影响力迅速减少,15 min时角膜形状已基本恢复。Objective Extraocular vacuum-suction often is performed in some treating procedure. However, whether vacuum-suction induce the change of corneal topography or was unclear. This study was to evaluate the effect of periodical vacuum-suction on corneal topography. Methods Forty eyes of 40 patients with extraocular counterpulsation for optical nerve disease were enrolled in the study. The extraocular vacuum suction was performed with the speed of 100 mmHg/3 seconds and the suction pressure of 300 - 20 mmHg for about 5 seconds,then the pressure was released to zero. The operation was carried out for 10 cycles at 1-minute interval. The topography was examined at 1 minute,5,15 minutes and the complaints of patients, visual acuity,intraocular pressure （lOP） were evaluated after suction respectively. The corneal irregularity measurement （CIM） , shape factor （SF）, corneal astigmatism （ASTIG） was analyzed before and after vacuum-suction. This study procedure followed the Statement of Helsinki,and the oral informed consent was obtained from individuals of participated in trial. Results Temporary rise of corneal astigmatism was found in 1 minute after vacuum-suction, and then declined gradually from 5 minutes through 15 minutes. There was a significant difference in ASTIG among different time before and after suction （ F = 7.62, P = 0. 006 ）. The ehange of CIM upon time after vacuum-suction followed the same pattern （ F = 0. 431 , P = 0. 001 ）. However, no significant difference was seen in SF before and after vacuum-suction （ F = 0. 635, P = 0. 050 2 ） . No significant correlations were found in eye departure,sex and ASTIG,CIM ,SF（ all P 〉 O. 05 ）. Four patients（ 10% ） complained of mild discomfort in eyes. Temporary vision blur occurred in 2 patients （5%） after suction. Slightly eonjunctival congestion was found in 15 eyes（37.5% ） and dotted epithelium missing in 1 （0.5%）. No IOP abnormality was found during the duration. Conclusion Periodical extraoeular vacuum-suction show

关 键 词：负压吸引 角膜地形 角膜不规则指数 形状因子 角膜散光 

分 类 号：R772[医药卫生—眼科]