粤东地区莱姆病血清流行病学调查  

Investigation on the Lyme Disease Populated in the Eastern Part of Guangdong Province (Three Counties in Meizhou City)

作　　者：郭衍[1,2,3] 万康林[1,2,3] 许世锷 陈慎奔[1,2,3] 潘林祥 张哲夫[1,2,3] 王宏英 廖传红[1,2,3] 谢霖崇 陈贵友 邓经谋[1,2,3] 姚良治 

机构地区：[1]汕头大学医学院 [2]中国预防医学科学院流行病学微生物学研究所 [3]广东省梅州市卫生防疫站

出　　处：《中国媒介生物学及控制杂志》1998年第4期261-264,共4页Chinese Journal of Vector Biology and Control

摘　　要：目的：检测健康人群血清莱姆病抗体水平。方法：间接免疫荧光抗体试验（ＩＦＡ）、酶联免疫吸附试验（ＥＬＩＳＡ）。结果：共检测２１８４人，阳性２２５人，感染率１０３０％。儿童（１３８５％）、学生（１１９３％）感染率最高，农民（１０５７％）次之，林业工人及管理人员（６４４％）相对较低；林区（１０３７％）与非林区（１０２７％）人群感染率差异无显著性（χ２＝０２１，Ｐ＞０７５）。１８０例莱姆病血清阳性者中，蜱叮咬率为４０％，未发现典型的慢性游走性红斑（ＥＣＭ）皮疹患者，红斑、风团、紫斑占３２７８％，肌痛占２３３３％，关节炎占４１１１％。Using IEA and ELISA, we examined the antibodies of Lyme disease populated in the eastern part of Guangdong province in 1994-1995 (three counties in Meizhou city). Of 2184 investigated people, 225 cases were infected, the rate of infection was 10.30%.The highest infection was in children, pupils, the second was peasants. The infective rate seems relatively lower among the workers and the administractive personel of the forest.There were no obvious differences in the population between the forest and the noforest area.In the individual investigation on the 180 antibody positive cases, we found 40.00% of them bitten by ticks, no typical ECM rash, 32.78% of them had specks, urticaria (nettle rash), purple specks, 23.33% muscle pain, 41.11% arthritis.The investigation proved the Lyme disease was present in the eastern part of Guangdong province, the subtropical area, the infective rate be high.

关 键 词：莱姆病 血清学 个案调查 流行病学 粤东地区 

分 类 号：R514.01[医药卫生—内科学] R377[医药卫生—临床医学]