清火片生产工艺优选  

Study on the production technology of Qinghuo tablets

作　　者：林小燕[1] 王文(石羡)[1] 

机构地区：[1]福建漳州职业技术学院,漳州363000

出　　处：《海峡药学》2009年第10期18-20,共3页Strait Pharmaceutical Journal

基　　金：漳州职业技术学院科研资助项目,项目编号:ZZY0811

摘　　要：目的摸索清火片的制备工艺,提高清火片的质量。方法以一步制粒法制备颗粒,并将薄荷脑用β-环糊精包合,制成包合物后加入压片。结果以该法制备的清火片,外观、成品颗粒、片剂崩解时限及包衣片的外观质量均优于传统制法。结论清火片工艺合理可行。OBJECTIVE To study the optimum preparation procedure of Qinghuo tablets and improve product quality.METHODS The granules were prepared by fluidized bed granulation.Bomeolum-β-cyclodextrin inclusion complex was produced and added into the compression process.RESULTS The production technology of Qinghuo tablets was better than the traditional one on appearance,semi-manufactured granules and disintegration test.CONCLUSION The production technology of qinghuo tablets is reasonable and stable.

关 键 词：清火片 一步制粒 Β-环糊精 包合 薄膜包衣 

分 类 号：TQ460.4[化学工程—制药化工]