34例非小细胞肺癌脑转移患者预后的回顾性分析  

Prognosis of 34 Cases with Brain Metastasis from Non-Small Cell Lung Cancer:A Retrospective Study

作　　者：李铮[1] 周云峰[1] 

机构地区：[1]武汉大学中南医院放化疗科,湖北武汉430071

出　　处：《武汉大学学报（医学版）》2009年第5期655-659,共5页Medical Journal of Wuhan University

摘　　要：目的:通过回顾性分析34例非小细胞肺癌患者的生存情况,探讨影响非小细胞肺癌脑转移预后的因素。方法:对34例非小细胞肺癌脑转移患者进行以全脑放疗为主,其他治疗为辅的综合治疗。结果:全组34例非小细胞肺癌脑转移患者总体生存期为4-88个月;总体中位生存期17个月,从发现脑转移-死亡的时间为1-33个月,中位生存期为5个月。结论:本组患者中对脑转移灶的治疗方式对生存期有影响,而脑转移灶放疗方式可能对预后存在影响。肺癌脑转移患者治疗应根据患者自身情况行综合性治疗。Objective： To review the outcomes of 34 patients with brain metastasis from non-small cell lung carcinoma （NSCLC）, and to investigate the related factors which would impact on the prog- nosis of NSCLC. Methods： From Apr 1994 to Nov 2005, 34 patients with brain metastasis from NSCLC accepted encephalic irradiation or combined with other therapies （such as neurosurgery, chemotherapy, etc）. Results： The overall median survival time was 17 months（ranged 4-88 months）, and the median survival time after brain metastases was five months （ranged 1-33 months）. Conclusion： The factors such as treatment methods for brain metastases had statistical effect on the survival rate, and the differents ways of irradiation for brain metastases also may have some influences on the outcome. So the NSCLC with brain metastases should be treated in ways differently according to different cases.

关 键 词：非小细胞肺癌 脑转移 回顾性分析 

分 类 号：R734.1[医药卫生—肿瘤]