绝经后妇女绒毛膜癌的临床分析  

Clinical Characteristics and Management of Choriocarcinoma in Postmenopausal Women

作　　者：庞晓燕[1] 张颐[1] 

机构地区：[1]中国医科大学附属第一医院妇科,沈阳110001

出　　处：《中国医科大学学报》2009年第10期773-774,780,共3页Journal of China Medical University

基　　金：辽宁省自然科学基金资助项目(20052116)

摘　　要：目的探讨绝经后妇女绒毛膜癌的临床特点及治疗转归。方法回顾性分析134例妊娠滋养细胞肿瘤中6例绝经后妇女绒毛膜癌患者的治疗过程及结果。结果绝经后绒毛膜癌患者的主要临床表现为绝经后阴道流血。6例患者均接受了化疗,其中4例行全子宫及双附件切除术。6例绒毛膜癌患者中,3例完全缓解,1例部分缓解,1例病情稳定,1例疾病进展。随访后1例死亡,2例失访,3例存活至今。结论绝经后阴道流血的患者应考虑妊娠滋养细胞肿瘤的可能。确诊后,应及早给予化疗,化疗后手术切除全子宫及双附件可以取得相对满意的治疗效果。Objective To investigate the clinical characteristics, management and prognosis of choriocarcinoma in postmenopausal women. Methods Six cases of ehoriocarcinoma in postmenopausal women were reviewed retrospectively. Results Four cases in the 6 patients presented with abnormal vaginal bleeding. All of the six cases received chemotherapy and four cases underwent hysterectomy. Three cases achieved complete remission, one partial remission, one stable condition, and one disease pragression.One case died, two cases lost follow-up and three cases survived as follow-up so far. Conchlsion The diagnosis of pregnancy-related disease should be considered in the elderly women presenting with abnormal vaginal bleeding.Once diagnosed,chemotherapy should be given as soon as possible. Satisfactory effects can be achieved with a combination therapy of chemotherapy and surgery.

关 键 词：绝经后妇女 绒毛膜癌 妊娠滋养细胞肿瘤 

分 类 号：R737.33[医药卫生—肿瘤]