105例早期乳腺癌保乳手术临床疗效评价  

Clinical analysis of efficacy results in 105 breast cancer patients treated with breast conserving surgery

作　　者：王东民[1] 叶京明[1] 刘荫华[1] 

机构地区：[1]北京大学第一医院乳腺外科,北京100034

出　　处：《中华乳腺病杂志（电子版）》2007年第3期33-35,共3页Chinese Journal of Breast Disease(Electronic Edition)

摘　　要：目的分析早期乳腺癌保乳治疗的近期疗效。方法回顾分析2001—2005年105例早期乳腺癌患者,在接受保留乳房手术、辅助放化疗后的生存率和美容效果。结果全部患者中位随访时间24个月(15～86个月),随访满3年患者47例,3年总生存率100%,无病生存率95.7%。局部复发2例,手术至复发时间平均为21个月。远处转移2例,均为骨转移,手术至远处转移中位时间为18个月。共对85例患者进行术后乳房外形评价,良好、中等、较差分别为47.1%、50.6%、2.6%。结论保乳治疗联合全乳放射治疗是一种安全、疗效确切的早期乳腺癌治疗方式,并可保持良好的乳房外形。Objective To study the short-term therapeutic effect of breast conserving surgery for patients with early stage breast cancer. Methods The survival rate, recurrence and shape were retrospectively analyzed in 105 patients with breast cancer who received breast conserving surgery and adjuvant radiotherapy from January, 2001 to December, 2005. Results The 105 patients with breast cancer received breast conserving surgery, fol- lowed by radiotherapy. All the patients were followed up for a median period of 24 months （15 -86 months） and the average of 37.4 months. Forty-seven cases were followed up over 3 years. The 3-year overall survival rate was 100% , and disease free survival rate was 95. 7% , 2 cases experienced local relapse. The ave-rage interval be- tween operation and relapse was 21 months. Distant bone metastases were found in 2 cases . The median interval between operation and metastasis was 18 months. The cosmetic results of 85 patients were evaluated as good 47.1% , fair 50.6% , and poor 2. 6% . Conclusions For early breast cancer patients, breast conserving surgery followed by radiotherapy can obtain excellent local control and good cosmetic results.

关 键 词：乳腺癌 保乳手术 

分 类 号：R737.9[医药卫生—肿瘤]