脉冲强磁场对小鼠移植性实体瘤杀伤作用的实验研究  被引量:2

INJOURIOUS EFFECT OF STRONG IMPULSE MAGNETICFIELD ON IMPLANTED SOLID TUMOR IN MICE

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作  者:胡大为 王群 高德奎 刘国津 

机构地区:[1]白求恩医科大学

出  处:《承德医学院学报》1998年第3期180-182,共3页Journal of Chengde Medical University

基  金:河北省卫生厅资助

摘  要:目的:探讨交变脉冲强磁场对肿瘤组织杀伤作用的机理。方法:应用交变脉冲强磁场对30只接种Louis肺癌的昆明小鼠作杀伤实验研究,对实验组与对照组荷瘤鼠抑瘤率和抑瘤曲线进行检测。结果:两组肿瘤生长曲线存在明显差异,P<0.05。两组肿瘤生长体积和肿瘤重量均存在明显差异,P<0.01。肿瘤体积抑制率为52.94%,肿瘤重量抑制率为37.24%。结论:证实交变脉冲强磁场对肿瘤组织细胞具有选择性杀伤作用和抑制肿瘤生长作用,提示脉冲强磁场可能成为治疗癌症的一个新的物理疗法。In order to investigate the mechanism of injurious effect of alternating impulse magnetic field on tumor,the studg was carried out via alternating impulse magnetic field in 30 Kunming mice inoculated with Louis Lung cancer.The tumorsuppressing rates and tumorsuppressing curves were observed in experimental group and control group.The results showed that there were significant differences in tumor growth curves(P<0.05),tumor weight and tumor volume (P<0.01) between the two groups.The tumorsuppressing rate in tumor volume and weight were 52.94% and 37.24% respectively.the results revealed selective injurious effect and  growth suppressing effect of alternating impulse magnetic field on tumor cells.Strong alternating impulse magnetic field may be a new therapeutic method of treating malignant tumors.

关 键 词:脉冲磁场 肿瘤 杀伤实验 

分 类 号:R730.59[医药卫生—肿瘤]

 

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