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机构地区:[1]广东医学院附属医院老年病科
出 处:《实用老年医学》1998年第4期165-166,共2页Practical Geriatrics
摘 要:目的观察根除Hp对老年人十二指肠溃疡再出血的影响。方法选择70例Hp感染十二指肠溃疡并出血的老年病人并随机分成A、B2组。A组应用奥美拉唑(洛赛克)、胶态次枸橼酸铋(德诺)胶囊和羟氨苄青霉素进行根除Hp治疗;B组单独用洛赛克治疗。4周后停药追踪观察18个月。结果2组溃疡愈合率分别为100%、96.1%,2者比较无显著性差异(P>0.05);A、B2组Hp根除率分别为85%和16.6%,2者比较有显著性差异(P<0.05)。随访18个月后,A、B2组再出血率分别为2.94%和28%,2者比较有显著性差异(P<0.05)。结论根除Hp对老年人十二指肠溃疡再出血有一定的预防作用。Objective To study the rates of rebleeding in the aged duodenal ulcer patients following eradication of H.pylori. Methods 70 elder patients with associatedH.pylori duodenal ulcer hemorrhage were randomly divided into two groups.The patients received Losec,DeNol plus Amoxicillin(Group A),or Losec alone(Group B)for 4 weeks.They were followed up for 18 months. Results The ulcer healing rates were 100%(Group A)and 967%(Group B);there was no significant difference between the two groups (P>005).H.Pylori eradication rates were 85%(Group A)and 166%(Group B).H.pylori eradication rates of Group A were significantly higher than that of Group B(P<005).Rebleeding rates were significantly lower in Group A(294%) than in Group B(P<005). Conclusion Eradication of H.pylori significantly reduces the rates of rebleeding in the aged duodenal ulcer patients.
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