利培酮与氯丙嗪治疗精神分裂症的随机对照研究  

Random comparing research on the treatment of schizophrenia by risperdone and chlorpromazine

作　　者：王立娜[1] 宋继育[1] 苏冈[1] 

机构地区：[1]天津市安定医院,天津300074

出　　处：《天津药学》1998年第3期57-60,共4页Tianjin Pharmacy

摘　　要：利培酮片和氯丙嗪片治疗精神分裂症病人，利培酮组30例，氯丙嗪组30例。经8周治疗，结果显示：利培酮与氯丙嗪疗效相似，但利培酮起效时间较氯丙嗪早。对阴性症状的疗效优于氯丙嗪，且锥体外系副反应、植物神经系统副反应、体位性低血压及药物性皮疹，心电图异常改变均较氯丙嗪少见。The article reported their clinical results of treating the schizophrenia patients with risperdone and chlorpromazine. In the sampling,there were 30 cases each in the risperdone group and the chlorpromazine group. The results after 8 weeks of treatment shown that risperdone and chlorpromazine had similar effects. However,compared to the chlorpromazine risperdone took less time to be effective,had better effects for negative symptom,less side effects on extrapyramid and vegetative nerve system and also led to less orthostatic hypotension, drug rash, and abnormal ECG.

关 键 词：精神分裂症 利培酮 氯丙嗪 治疗 

分 类 号：R749.305[医药卫生—神经病学与精神病学]