抽动障碍(TD)儿童脑电特征及脑功能研究  

Study on EEG Characteristics and Brain Function of Children with tic Disorders

作　　者：王平[1] 范松丽[2] 李进华[2] 闫承生[2] 蒋燕清[2] 尚煜[2] 刘静[2] 袁文星[2] 陈卫红[2] 

机构地区：[1]中国.河北省唐山市妇幼保健院,063000 [2]河北省妇幼保健中心

出　　处：《中国健康心理学杂志》2009年第10期1169-1171,共3页China Journal of Health Psychology

基　　金：河北省科技攻关项目:抽动障碍(TD)的脑电图和脑电功能病例对照研究编号05276133

摘　　要：目的比较TD儿童与对照组儿童脑电图、脑功能的特征及智力情况,探讨抽动障碍(TD)儿童的脑功能特征及可能影响儿童智力的因素。方法采用病例对照研究方法,以4～15岁126例TD儿童及81例对照组儿童作为研究对象,所有儿童都进行脑电图及额部脑功能检查,并进行中国比内智力测验。结果1TD组额部脑电频率均慢于对照组(P<0.05),右前额明显(P<0.05);2TD组前额θ波脑电功率及θ/SMR、θ/β、α/SMR、α/β脑电功率比值均高于对照组;3TD组儿童前额脑电频率与前额θ波、前额θ/β脑电功率比值有负相关关系;4TD组儿童智商低于对照组。结论本研究显示TD儿童的脑电活动落后于正常对照组儿童,尤其是前额叶功能不足,智力低于正常儿童。Objective To compare EEG, brain function and intelligence between children with tic disorder （TD） and children in control group so as to explore characteristics of brain function of children with TD and factors affecting children＇s intelligence. Methods The case-control study was applied in which participants were 4-15 year-old who were tested by Stanford-Binet intelligence scale. The study included 126 cases with TD and 81 cases in control group. Results ①Frontal EEG frequencies of TD group were slower than those of control group （P〈0.05） and it was more obviously in right forehead. ②θ wave EEG power and θ/SMR, θ/β, α/SMR, α/β in forehead of TD group were higher than those of Control group. ③It was the negative correlation between EEG frequency and θ wave and θ/β ratio in forehead.④Intelligence quotient of TD group was lower than that of control group. Conclusion The study revealed that brain electrical activity and intelligence of children with TD fell behind the normal children of control group, especially the lack of prefrontal function.

关 键 词：精神病与精神卫生 儿童抽动障碍 病例对照研究 脑电频率 智力 

分 类 号：R741.044[医药卫生—神经病学与精神病学] R179[医药卫生—临床医学]