蕲蛇酶治疗急性脑梗死50例疗效观察  

Observation of Curative Effect of Agkistrodonase to Treat Acute Cerebral Infarction

作　　者：韩威[1] 

机构地区：[1]黑龙江省森工总医院神经内科,黑龙江哈尔滨150040

出　　处：《黑龙江医学》2009年第11期832-833,共2页Heilongjiang Medical Journal

摘　　要：目的观察蕲蛇酶治疗急性脑梗死的临床疗效。方法选用一般情况具有可比性的急性脑梗死患者,随机分成两组,治疗组50例,对照组45例。治疗组用蕲蛇酶0.75 U加生理盐水250 mL,静脉滴注,1次/d;对照组给予低分子右旋糖酐500 mL+复方丹参20 mL,静脉滴注,1次/d,两组疗程均为14 d。结果治疗组总有效率92%,对照组78%;两组治疗前神经功能缺损评分无显著差异(P>0.05),治疗14 d后,两组评分较前明显下降,但以蕲蛇酶治疗组下降显著,治疗后两组平均评分有显著性差异(P<0.01)。结论蕲蛇酶治疗急性脑梗死是安全有效的,可使急性脑梗死患者临床症状显著改善。Objective To observe the curative effect of agkistrodonase to treat ACI. Methods The ACI patients whose were comparative in general situation were divided into lwo groups（ therapy group 50 cases and control group 45 cases）. Tile therapy group was t^ated with agkistrodonase 0.75 U drip per day. The control group was treated with D - 40 500mL and complex radix 20mL as course of two weeks. Results The total effective rate was 92 % in therapy group and 78 ℃ in control group. The nerve function before treatment without difference had decreased after treatment with P 〈 0.01 especially in therapy group. Conclusion This drug might be safe and effective to treat ACI and improve the symptoms.

关 键 词：蕲蛇酶 脑梗死 疗效对比 

分 类 号：R743.33[医药卫生—神经病学与精神病学]