52例胃肠道间质瘤的临床诊治及病理学分析  

Clinical diagnosis and treatment and pathological analysis of 52 cases with gastrointestinal stromal tumors

作　　者：王军[1] 赵端仪[1] 罗先文[1] 岳奇俊[1] 魏莱[1] 彭莉娜[1] 孙宏斌[1] 张政[1] 

机构地区：[1]武警湖北总队医院胃肠外科,武汉430061

出　　处：《国际外科学杂志》2009年第11期736-738,共3页International Journal of Surgery

摘　　要：目的探讨胃肠道间质瘤（GIST）的临床表现和诊治方法及病理、免疫组化特征。方法对1995年1月至2007年12月武警湖北总队医院收治的52例胃肠道间质瘤患者进行回顾性分析，分析其临床治疗及病理学特征。结果本组52例胃肠道间质瘤患者均接受手术治疗，其中45例为完全切除。52例患者中CD117阳性表达52例（100％），CD34阳性表达46例（88．5％）。结论GIST以外科手术切除为主，完全切除很重要。GIST术前确诊率低，其确诊依赖免疫病理结果，CD117和CD34联合使用可协助诊断GIST。Objective To investigate clinical manifestations and clinical diagnosis and treatment and pathological and immunohistochemical features in gastrointestinal stromal tumors. Methods The clinical data of fifty-two cases with gastrointestinal stromal tumors were collected, whose clinical diagnosis and treatment and pathological features were retrospectively analyzed from January 1995 to December 2007. Results All patients received operation therapy, only forty-five cases with complete surgical resection. The immunohistochemical staining showed that the cases with CD117 positive accounted for 100% （52/52） and CD34 positive accounted for 88.5% （46/52）. Conclusions Surgery was necessary for all patients, especially complete surgical resection. Gastrointestinal stromal tumors were poor in preoperative diagnosis, which diag- nosis was based on the immunohistochemical staining of the tumor tissue. CD117 and CD34 tumor markers may help to diagnose gastrointestinal stromal tumors.

关 键 词：胃肠间质瘤 外科治疗 病理学 

分 类 号：R735[医药卫生—肿瘤] R361.1[医药卫生—临床医学]