维、汉族缺血性脑血管病患者颅内外动脉狭窄的发生率、分布及危险因素  

Incidence,distribution and risk factors of intracranial and extracranial artery stenosis in Uygur and Han patients with ischemic cerebrovascular disease

作　　者：蔡俊秀[1] 张小宁[2] 

机构地区：[1]新疆医科大学第五附属医院神经内科,乌鲁木齐830011 [2]新疆医科大学第一附属医院神经内科

出　　处：《临床神经病学杂志》2009年第5期340-343,共4页Journal of Clinical Neurology

基　　金：新疆自治区科技攻关和重点项目计划(200733146)

摘　　要：目的探讨维、汉族缺血性脑血管病（ICVD）患者颅内外动脉狭窄的发生率、分布及危险因素。方法对165例汉族、108例维族ICVD患者行DSA检查,以及血糖、血脂水平检查。对两组患者的颅内外动脉狭窄发生率、分布特点和脑卒中危险因素进行统计分析。结果汉族组有颅内外动脉狭窄103例（62.4%）,维族组为70例（64.8%）,两组差异无统计学意义。汉族组与维族组颅内动脉、颅外动脉及颅内外动脉狭窄的比率差异无统计学意义。汉族组患者颅内外动脉狭窄与年龄、高血压、吸烟、低高密度脂蛋白（HDL）血症有关（P〈0.05-0.01）;维族组患者动脉狭窄与年龄、高血压、糖尿病、高三酰甘油（TG）血症有关（均P〈0.05）。Logistic多因素回归分析显示,年龄、高血压、低HDL血症是汉族组颅内外动脉狭窄的独立危险因素（P〈0.05-0.01）;而维族组的则为高血压、糖尿病、高TG血症（均P〈0.05）。结论维、汉族ICVD患者颅内外动脉狭窄的发生率及分布差异无统计学意义;高血压是维、汉族ICVD患者颅内外动脉狭窄的共同的独立危险因素,而年龄、低HDL血症和糖尿病、高TG血症则分别是汉族和维族的独立危险因素。Objective To explore the incidence,distribution and the risk factors of intracranial and extracranial artery stenosis in patients with isehcmic cerebrovascular disease（ ICVD） in Uygur and Han. Methods Both 165 Han and 108 Uygur patients of 1CVD were detected by using DSA. The level of serum glucose and lipidemia were measured. Statistical analysis was used to evaluate the incidence, distribution and risk fators of intracranial and extracranial artery stenosis in Hart and Uygur groups. Results 103 （62.4%） cases in Han group and 70（ 64.8% ） cases in Uygur group existed intracranial and extracranial artery stenosis, but there was no significantly difference between the two groups. There was no significantly difference in the distribution of cerebral arterial stenosis between Han and Uygur groups. In Han group, age, hypertension, smoking and low HDL were related to cerebral arterial stenosis（ P〈 0. 05 - 0.01 ）. In Uygur group,age, hypertension, diabetes mellitus and high TG were related to cerebral arterial stenosis （all P 〈 0. 05 ）. The logistic regression showed that age, hypertension and low HDL were independent risk factors in Han group （ P 〈 0.05 - 0. 01 ） ; diabetes mellitus, hypertension and high TG were independent risk factors in Uygur group （all P 〈 0. 05 ）. Conclusion There is no significant difference in the incidence and distribution of intracranial and extracranial artery stenosis in patients with ICVD between Uygur and Han. Hypertension is which common and independent risk factors in Uygur and Han ICVD patients; age, low HDL and diabetes mellitus, high TG are the risk factors in Han and Uygur respectively.

关 键 词：维族 汉族 颅内外动脉狭窄 缺血性脑血管病 危险因素 

分 类 号：R743.3[医药卫生—神经病学与精神病学]