113例已婚妇女生殖道念珠菌健康携带情况及药敏分析  

Analysis of Healthy Carrying State and Antifungal Susceptibility of Candida Species Isolated from Genital Tract among 113 Married Women

作　　者：郭利军[1] 武有聪[1] 白丽[1] 梅娟娟[1] 

机构地区：[1]大理学院基础医学院,云南大理671000

出　　处：《大理学院学报（综合版）》2009年第10期34-36,共3页Journal of Dali University

基　　金：云南省教育厅科研基金资助项目(04Y196C)

摘　　要：目的:了解已婚妇女生殖道念珠菌健康携带状况及菌群分布、对常用抗真菌药物的敏感性。方法:采取健康已婚妇女生殖道分泌物进行念珠菌分离培养、鉴定和药物敏感性试验。结果:113份标本中检出念珠菌22株,其中以白念珠菌为主(50%),光滑念珠菌7株、克柔念珠菌2株、其它念珠菌2株。汉族和少数民族已婚妇女生殖道标本各检出念珠菌11株;检出的念珠菌对酮康唑(KETO)、氟康唑(FCZ)、5-氟胞嘧啶(5-FC)和两性霉素-B(B AMB)的耐药株数分别为10、6、2和1株。结论:本次调查的已婚妇女生殖道念珠菌健康携带率为19.5%,部分念珠菌对常用抗真菌药物存在耐药现象。Objective： To realize healthy carrying state, distribution and susceptibility of Candida species against common antifungal drugs from genital tract among 113 married women. Methods： Collecting cervical secretions from married women in their healthy physical examination and to cultivate these specimens for isolation, identification and antifungal susceptibility test of Candida species. Results： 22 Candida species were detected among 113 specimens and there were 11 strains of Candida albicans （50%）, 7 strains of Candida glabrata, 2 strains of Candida krusei, 2 strains of other Candida species. 11 Candida species were isolated from genital tract of Han and minority nationality women, respectively. The number of resistant strains against KETO, FCZ, 5-FC and AMB was 10, 6, 2 and 1, respectively. Conclusions： The Candida healthy cartier rate of married women genital tract was 19.5%. There exists resistant phenomenon of Candida species against common antifungal drugs.

关 键 词：携带率 菌株分布 药物敏感性 念珠菌 已婚妇女 

分 类 号：R379.3[医药卫生—病原生物学]