早产与牙周疾病关系的巢式病例对照研究  

Nested case-control study on the relationship between premature delivery and periodontal diseases

作　　者：徐金龙[1] 朱宁湖[2] 胡庆[1] 

机构地区：[1]广东省妇幼保健院口腔科,广州510010 [2]广东省妇幼保健院产科,广州510010

出　　处：《中华口腔医学研究杂志（电子版）》2009年第5期53-55,共3页Chinese Journal of Stomatological Research(Electronic Edition)

基　　金：广东省医学科研基金(A2008086)

摘　　要：目的探讨牙周疾病与早产的关系。方法采用巢式病例对照研究设计,对480名孕产妇进行随访观察和配对病例对照研究,配对Logistic回归分析方法分析早产和牙周疾病的关系。结果牙周病组孕产妇的早产发生率为27.5%,非牙周病组为5.42%,两者比较差异有统计学意义(P<0.01)。牙周病组发生早产的优势比为4.67。结论牙周病是造成早产的危险因素之一。Objective To study the relationship between premature delivery and periodontal diseases. Methods A nested case control study was carried out in 480 pregnant women to compare the pre-term delivery rate between the periodontal disease and non- group. Then, paired case-control study and conditioned logistic regression were applied to analyze the relationship between premature delivery and periodontal diseases. Results Pre-term delivery occurred in 27.5% of women associated with periodontal diseases while only 5.42% in non-periodontal disease group. Pregnant women with periodontal disease had a higher frequency of pre-term delivery （P 〈 0.01）, the odds ratio （OR） being 4.67. Conclusion Periodontal diseases was one of the risk factors to premature delivery.

关 键 词：早产 牙周病 

分 类 号：R781.4[医药卫生—口腔医学] R722.6[医药卫生—临床医学]