儿童视觉发育敏感期微视觉诱发电位研究  

Mini visual evoked optential in infants during their sensitive period of visual development

作　　者：周炼红[1] 朱祥祥[1] 邢怡桥[1] 易莲芳[1] 王炯[1] 吴丽[1] 

机构地区：[1]武汉大学人民医院眼科,430060

出　　处：《中华眼底病杂志》2009年第6期440-442,共3页Chinese Journal of Ocular Fundus Diseases

摘　　要：目的 观察不同年龄儿童微视觉诱发电位（miniVEP）的潜伏期和振幅值变化。方法 对随机选取的84名正常儿童和正常成年人的168只眼进行miniVEP检测。所有受试者按年龄分为A组：0-3个月；B组：4-6个月；C组：7-12个月；D组：1-3岁；E组：4-6岁；F组：7-12岁。G组：对照组，正常成年人。每组均为12人24只眼。采用德国Roland 电生理仪，使用miniVEP刺激器行闪光VEP（F-VEP）检查，分析P100波波形、振幅高低及潜伏期时程长短。结果 Ａ组振幅平均值最低，潜伏期平均值最大，分别为（7.39±1.79） μV和（137.45±7.64） ms；A、B、C、D、E组振幅平均值依次增高（F=359.56），A、B、C、D组潜伏期平均值依次缩短（F=326.64），差异有统计学意义（P〈0.01）；E、F、G组振幅均较高，3组之间差异无统计学意义（F=2.39，P〉0.05）；D、E、F、G组潜伏期均较短，4组之间差异无统计学意义（F=2.64，P〉0.05）。结论 儿童随着年龄增长, 振幅增高，潜伏期缩短，潜伏期的发育先于振幅达到成人水平。Objective To observe the changes of amplitude and latency of mini visual evoked optential （mini VEP） examinations in infants at different age.Methods A total of 84 healthy infants and adults （168 eyes） were randomly selected to underwent mini VEP. According to the age, all the individuals were divided into seven groups： A, 0-3 months; B, 4-6 months; C： 7-12 months; D： 1-3 years; E： 4-6 years; F： 7-12 years; G： adults （control）. There were 12 individuals （24 eyes） in each group. By using the stimulater of mini VEP, the flash VEP was performed and the changes of amplitude and latency of P100 wave were recorded and analyzed.Results The average value of amplitude in group A was（7.39±1.79）μV which was the lowest, and the average latency was （137.45±7.64）ms which was the largest.At the same time, the average amplitude of P100 increased from group A to E （F=359.56）; the average latency decreased from Group A to D（F=326.64）; the difference was significant （P〈0.01）. The amplitude in group E, F, and G was high and no significant difference was found （F=2.39,P〉0.05）;the latency in group D,E,F,and G was short with no significant difference （F=2.64,P〉0.05）.Conclusions With the growth of the infants＇ age, the amplitude of miniVEP increases and latency decreases; moreover, the latency reaches the normal adult level in advance of the amplitude of miniVEP.

关 键 词：诱发电位 视觉 儿童 

分 类 号：R779.7[医药卫生—眼科]