载银纳米二氧化钛树脂基托光触媒的抗真菌作用  

Antibacterial efficacy of photocatalytic material on the resin base with Ag-embedded nano-TiO_2

作　　者：李斌[1] 任艳云[1] 徐立群[1] 石兰[1] 李广毅[1] 

机构地区：[1]解放军第117医院口腔科,浙江杭州310013

出　　处：《中国美容医学》2009年第11期1657-1659,共3页Chinese Journal of Aesthetic Medicine

基　　金：南京军区卫生科研项目(08MB147)

摘　　要：目的:观察载银纳米二氧化钛树脂(聚甲基丙烯酸甲酯)基托中二氧化钛光触媒的抗真菌作用。方法:采用肉汤稀释法测定载银纳米二氧化钛抗菌粉对白色念珠菌的最小抑菌浓度(MIC);测定等量载银纳米二氧化钛、纳米二氧化钛树脂基托在无光及日光灯照下对白色念珠菌的抗菌率,并对其进行对比。结果:载银纳米二氧化钛抗菌粉对白色念珠菌的最小抑菌浓度为20g/L;当载银纳米二氧化钛抗菌粉在树脂基托中的浓度为20g/L时,无光及光照条件下其对白色念珠菌的抗菌率分别为50.1%,91.5%。等质量纳米二氧化钛在无光及光照条件下其对白色念珠菌的抗菌率分别为1.5%、61.9%。结论:纳米二氧化钛只有在光照条件下方可显示出抑菌作用,纳米银不经光照具有抑菌作用;载银纳米二氧化钛兼具两者的优点,具有广泛的应用前景。Objective To observe the antibacterial of photocatalytic material on poly methyl methacrylate denture base with Ag-embedded nano-TiO2 in vitro. Methods Minimum inhibitory concentration （MIC） of the denture base with Ag- embedded nano-TiO2 against Candida albicans was examined by broth dilution method , According to the MIC,the antimicrobial effect of resin bases with Ag-embedded nano-TiO2 or nano-titanium dioxide were examined and contrasted in the dark and under fluorescent lamp. Results The MIC of the Ag-embedded nano-TiO2 against Candida albicans was 20g/L.When containing anti-bacterial Ag-embedded nano-TiO2 powder in the resin base of the concentration of 20g/L,the Dark and light conditions on Candida albicans anti-bacterial rates were 50.1%,91.5%. The anti-bacterial rate against Candida albicans of resin bases with nano-titanium dioxide were 1.5% and 61.9%. Conclusion The resin bases with nano-titanium dioxide only in the light conditions, can be shown Bacteriostasis against Candida albicans,The resin bases with Ag-embedded nano-TiO2 have good bacteriostasis against Candida albicans both in dark and in light,with a wide range of applications.

关 键 词：光触媒 载银纳米二氧化钛 抗菌 白色念珠菌 

分 类 号：R783[医药卫生—口腔医学]