胰腺实性-假乳头状瘤1例病案报道及文献回顾  

Solid-pseudopapillary tumor of the pancreas:one case report and literature review

作　　者：张力[1] 巩丽[1] 韩秀娟[1] 刘小艳[1] 朱少君[1] 兰淼[1] 张伟[1] 

机构地区：[1]第四军医大学唐都医院病理科,陕西西安710038

出　　处：《现代肿瘤医学》2009年第11期2169-2171,共3页Journal of Modern Oncology

摘　　要：目的:报道1例胰腺实性-假乳头状瘤,结合文献探讨其临床病理学特征、诊断及鉴别诊断要点。方法:对1例胰腺实性-假乳头状瘤进行临床病理分析及免疫组化观察。结果:胰腺实性-假乳头状瘤患者无特异性临床表现及体征,多在体检或其他原因开腹探查时偶被发现。镜下可见肿瘤由实性区、假乳头状区及囊性区混合组成,细胞形态一致、无异型的瘤细胞排列呈片状和假乳头状,肿瘤细胞围绕血管蒂呈复层排列成假乳头状突起为其特征。免疫组化染色结果:肿瘤细胞表达Vim、Syn,NSE;不表达PR、CEA、S-100、CK、CA19-9、EMA。结论:胰腺实性-假乳头状瘤好发于年轻女性,具有独特的临床病理特点,其诊断和鉴别诊断主要依靠病理组织学和免疫组化,治疗以手术切除为主,预后较好。Objective ：To report one case of solid - pseudopapillary tumor （SPT） of the pancreas and discuss its clinical and histopathologic features,diagnosis and differential diagnosis. Methods： One case of SPT was analyzed by means of clinicopathology and immunohistochemistry. Results ： Patients with SPT had no special clinical and physical sign. They were occasionally found in health examination and abdominal surgial exploration for other reasons. Micro- scopically, the lesion was composed of solid, pseudo - papillary and cystical area. It was observed that the tumor cells were located in a pseudopapillary pattern with a fibrovascular core histologically. Immunohistochemically, the tumor ceils were positive for Vim, Syn, NSE, but negative for PR, CEA, S - 100, CK, CA19 - 9, EMA. Conclusion： SPT, with special clinicopathological features, occurs usually in young female. The diagnosis and differential diagnosis of SPT mainly rely on histopathological and immunohistochemical findings. The surgical excision is the main treatment method, and have excellent prognosis.

关 键 词：胰腺 实性-假乳头状瘤 临床病理 

分 类 号：R735.9[医药卫生—肿瘤]