多发性骨髓瘤常用实验诊断方法评价  

Evaluation of labouratory tests for diagnosis of multiple myeloma

作　　者：顾炳权[1] 苏海鹏[1] 董轲[1] 孙晓红[1] 张静[1] 张惠中[1] 

机构地区：[1]第四军医大学唐都医院检验科,陕西西安710038

出　　处：《现代肿瘤医学》2009年第11期2217-2219,共3页Journal of Modern Oncology

摘　　要：目的:比较血清蛋白电泳(琼脂糖凝胶法)、尿本周氏蛋白、骨髓细胞学等实验室指标对多发性骨髓瘤的诊断价值,找出经济、简便、快速的敏感指标。方法:分析多发性骨髓瘤的诊断过程,计算血清蛋白电泳、尿本周氏蛋白、骨髓细胞学诊断的敏感度和特异度。结果:琼脂糖凝胶血清蛋白电泳的敏感度是96.6%,特异度96.4%;尿本周氏蛋白的敏感度是10.5%,特异度98.2%;骨髓细胞学的敏感度是51.7%,特异度100%。.结论:琼脂糖凝胶血清蛋白电泳的敏感度最高,且简便、快速、经济实用。Objective：To evaluate the valus of serum protein electrophoresis （agarose gel）, Bence -jones protein, bonemarrow cytology tests in multiple myeloma（MM） diagnosis. Methods：To analyze the diagnosis of MM,calculate the sensitivity and sptcificity of serum protein electrophoresis, Bence -jones protein and bone marrow cytology of. Results：The sensitivity of the serum protein gel electrophoresis was 96.6% ,and the specificity was 96.4% ;Bence -jones protein sensitivity was 10.5 %, specificity was 98.2% ;bone marrow cytology sensitivity was 51.7 % and specificity 100%. Conclusion： The serum protein gel electrophoresis test is with the highest sensitivity, and simple, quick, economical and practical for the diagnosis of MM.

关 键 词：多发性骨髓瘤 血清蛋白电泳 敏感度 特异度 

分 类 号：R733.3[医药卫生—肿瘤]