儿童眼部肿瘤临床病理分析234例  

Pathological analysis of ocular tumor in 234 children

作　　者：蒋永强[1] 陆方[1] 吴晓梅 夏瑞南 

机构地区：[1]四川大学华西临床医学院眼科,四川省成都市610041

出　　处：《眼科新进展》2009年第11期858-860,共3页Recent Advances in Ophthalmology

摘　　要：目的分析儿童眼部肿瘤的发病特点。方法对我院眼科1998年1月至2008年5月收治并经病理学证实的234例儿童眼部肿瘤患者的肿瘤发生部位及病理类型进行回顾性分析。结果按肿瘤的发病部位分为:眼睑肿瘤79例(33.8%),结膜肿瘤44例(18.8%),眼球内肿瘤44例(18.8%),眼眶肿瘤40例(17.1%),角膜肿瘤21例(9.0%),视神经肿瘤6例(2.6%);按肿瘤的性质及病理类型分:良性187例(79.9%),恶性47例(20.1%)。良性肿瘤中常见的有色素痣瘤42例(22.4%),炎性增生瘤32例(17.1%),皮样囊肿25例(13.4%),皮样瘤20例(10.7%),血管瘤17例(9.1%),乳头状瘤8例(4.3%),迷芽瘤7例(3.7%),视神经胶质瘤6例(3.2%);恶性肿瘤常见的有视网膜母细胞瘤37例(78.7%),胚胎型横纹肌肉瘤7例(14.9%)。结论儿童眼部肿瘤的特点和成人明显不同,大多数为先天性和胚胎性;其中眼睑肿瘤发生率最高,眼眶肿瘤的病理类型最多达16种;良性肿瘤中色素痣的发病率最高,其次为炎性增生、皮样囊肿和皮样瘤;恶性肿瘤中视网膜母细胞瘤发病率最高,其次为横纹肌肉瘤。Objective To explore the pathogenetic characteristics of ocular tumor in children.Methods Retrospective analysis was taken in tumor location and pathological types of 234 children with ocular tumor,who were pathologically confirmed and treated in our hospital from January,1998 to May,2008.Results According to tumor location,79 cases were eyelid tumor（33.8%）,44 cases were conjunctival tumor（18.8%）,44 cases were intraocular tumor（18.8%）,40 cases were orbital tumor（17.1%）,21 cases were corneal tumor（9.0%）,6 cases were optic nerve tumor（2.6%）.According to the characteristics and pathological types of tumor,187 ocular tumors（79.9%） were benign and 47 ocular tumors（20.1%） were malignant.The common benign tumors were nevus tumor in 42 cases（22.4%）,inflammatory hyperplasia in 32 cases（17.1%）,dermoid cyst in 25 cases（13.4%）,dermoid tumor in 20 cases（10.7%）,hemangioma in 17 cases（9.1%）,papilloma in 8 cases（4.3%）,choristoma in 7 cases（3.7%） and glioma of optic nerve in 6 cases（3.2%）.The common malignant tumors were retinoblastoma in 37 cases（78.7%） and embryonic rhabdomyosarcoma in 7 cases（14.9%）.Conclusions Ocular tumors of children are distinct from those of adults,and most are congenital and embryonic tumors.The most common ocular tumor in 234 children patients is the eyelid tumor.Eyelid tumor is with the highest incidence rate.The pathological types of orbital tumor are the most about 16 types.Nevus tumor is with the highest incidence rate in benign tumors,followed by inflammatory hyperplasia,dermoid cyst and dermoid tumor.Among the malignant tumors,retinoblastoma is with the highest incidence rate,followed by rhabdomyosarcoma.

关 键 词：儿童 眼部肿瘤 病理分析 

分 类 号：R77[医药卫生—眼科]