宫颈癌后装治疗用甘氨双唑钠增敏40例  

The effect of CMNa for cervical carcinoma patients treated by brachytherapy

作　　者：秦日昇[1] 徐李容[1] 彭丽芳[1] 申昊[1] 

机构地区：[1]广西壮族自治区南溪山医院放疗二区,广西桂林541002

出　　处：《现代肿瘤医学》2009年第12期2413-2414,共2页Journal of Modern Oncology

摘　　要：目的:探讨宫颈癌患者后装治疗用甘氨双唑钠放射治疗的增敏作用。方法:85例接受放射治疗的宫颈癌患者,随机分为增敏组40例和常规组45例,常规组常规放疗,增敏组放疗方案同常规组,但后装治疗时用甘氨双唑钠增敏。结果:增敏组肿瘤完全消退38例(95%),肿瘤消退平均后装次数2.9次,优于常规组肿瘤完全消退35例(85%),肿瘤消退平均后装次数4.5次(P<0.05),肿瘤消退时间约提前1.6周。两组急性放射性肠炎、骨髓抑制发生率无统计学差异。结论:后装治疗前使用甘氨双唑钠可达放射增敏目的。Objective：To explore the effect of radiosensitizer（CMNa） for cervical carcinoma patients. Metheds： All 85 patients were enrolled into two groups ： control group 45 cases received radiotherapy alone; radiosensitize group 40 cases received radiotherapy add radiosensitizer （CMNa） （ only braehy - therapy add CMNa）. Results： CR in the radiosensitize group was 95% , in the control group was 85%, （P 〈 0.05 ） , the time reaching CR in the radiosensitize group was shorter;virulent radiation enterocolitis and blood toxicity in two groups were resembled. Conclusion：CMNa can increase cervical tumor radiosensitivity in brachytherapy.

关 键 词：宫颈肿瘤 放射疗法 甘氨双唑钠 后装治疗 

分 类 号：R737.3[医药卫生—肿瘤]