髌骨软骨母细胞瘤临床病理观察  

Clinicopathologic features of chondroblastoma in patella

作　　者：杨艳丽[1] 刘斌[1] 邢传平[1] 哈英娣[1] 苏勤军[1] 高自芳[1] 

机构地区：[1]兰州军区总医院病理科,兰州730050

出　　处：《诊断病理学杂志》2009年第5期361-364,共4页Chinese Journal of Diagnostic Pathology

摘　　要：目的探讨髌骨软骨母细胞瘤(CB)的临床特点、病理形态、免疫表型、影像学及预后。方法报告1例髌骨软骨母细胞瘤,复习近38年国内外有关文献报道,分析髌CB瘤的临床、病理和影像的诊断与鉴别诊断及预后资料。结果患者男性,21岁。左膝部疼痛伴左下肢无力半年。X线片可见髌骨内溶骨性破坏。镜下肿瘤由圆形或多角形软骨母细胞、多核巨细胞、局灶样类软骨组织及小的钙化灶等成分组成,瘤组织S-100(+)。结论软骨母细胞瘤发生在髌骨甚为罕见,其发生率约占软骨母细胞瘤的2%,因其在组织学上表现的多样性应临床、病理学、影像学检查三结合进行诊断。Objective To investigate the clinicopathological and immtmohistochemical features and imaging changes as well as its prognosis of chondroblastoma in the patella. Methods The literatures related to chondroblastoma in patella during recent three decades were reviewed and a case was reported. Meanwhile, the diagnosis and differential diagnosis, clinicopathological and immunohistochemical features as well as image changes were analyzed. Results This case is a 21-year-old man with left knee pain associated with acratia of left lower extremity in half a year. Radiologic features showed the lesion was lyric in the inner of the patella. Histologic feature of chondroblastoma included sheets of closely packed retmdish or polygonal chondroblastic cells with interspersed multinucleated giant cells and islands of hypocellttlar eosinophilic cartilage matrix, focal areas of dystrophic calcification, S-100 （ ＋ ）. Conclusion The chondroblastoma occurred in the ptella is rare and its estimated incidence is about 2% in chondroblastoma. The tumor shows pleomorphic and its diagnosis must incorporate the clinical, pathologic features as well as its image changes.

关 键 词：髌骨 软骨母细胞瘤 免疫组化 

分 类 号：R738.1[医药卫生—肿瘤]