脑静脉系统血栓形成43例临床分析  

Clinical analysis of forty-three cases of cerebral venous thrombosis

作　　者：吴琪[1] 郑一帆[1] 陈玲[1] 方莹莹[1] 黄林欢[1] 黎锦如[1] 梁秀龄[1] 

机构地区：[1]中山大学附属第一医院神经科,广州510080

出　　处：《中国神经精神疾病杂志》2009年第11期667-669,共3页Chinese Journal of Nervous and Mental Diseases

摘　　要：目的探讨脑静脉系统血栓形成(cerebral venous thrombosis,CVT)的病因、临床特征、诊断及治疗。方法回顾性分析43例CVT患者临床资料,总结CVT的临床特点、影像学特征、诊断、治疗及转归。结果CVT多见于中青年,多为急性起病,大部分可找到相关病因,最常见的首发症状为头痛,MRI联合MRV能清晰地显示静脉系统形态及阻塞情况,DSA能清楚显示静脉系统血栓的部位及继发于CVT的动静脉瘘。早期诊断及应用抗凝治疗是取得良好预后的关键。结论CVT的病因多样,临床表现缺乏特异性,MRI联合MRV检查是目前CVT诊断及随访的重要检查方法,对原因不明的颅内高压患者需行相应检查,一旦确诊,应予抗凝治疗。Objective To explore the etiologies, clinical features, diagnosis and therapy of cerebral venous thrombosis （CVT）. Methods Forty-three cases of CVT were reviewed. The etiologies, clinical manifestations, imaging, diagnosis and treatment were analyzed. Results CVT was more frequent in young patients. The onset was acute and the etiologies could be found in majority of cases. Headache was the most common primary manifestation. MRI combined with MRV could demonstrate the pattern and the occlusion of the venous system clearly. DSA could clearly show the localization of the thrombosis and the arteriovenous fistula secondary to CVT. Early diagnosis and therapy by heparin were important for good prognosis. Conclusions The etiology of CVT is various and the manifestations of CVT are not typical. MRI, combined with MRV, is now very important for the diagnosis and follow-up should be carried out in CVT patients with unreasonable intracranial hypertension. Anticoagulation therapy should be used once the diagnosis is established.

关 键 词：脑静脉系统血栓形成 病因 临床特点 诊断 治疗 

分 类 号：R743.32[医药卫生—神经病学与精神病学]