响应面法优化莽草酸微波辅助提取工艺  

Optimization of microwave assisted extraction process of shikimic acid by response surface analysis methodology

作　　者：姚菁华[1] 肖雷[1] 李慧蓉[1] 吕小妹[1] 

机构地区：[1]中国矿业大学化工学院,江苏徐州221116

出　　处：《北京化工大学学报（自然科学版）》2009年第B11期14-17,共4页Journal of Beijing University of Chemical Technology(Natural Science Edition)

基　　金：国家"973"计划(2007CB210205);徐州市社会发展基金(xj08086);中国矿业大学大学生科研训练基金(080603)

摘　　要：为优化八角茴香中莽草酸的微波提取工艺,在单因素实验基础上,选择微波提取时间、微波功率、液料比(mL/g)为自变量,莽草酸得率作为响应值,采用中心组合设计的方法,研究各自变量及其交互作用对莽草酸提取的影响。采用响应面分析软件,模拟得到二次多项式回归方程的预测模型,并确定微波提取最佳工艺条件为时间19min、微波功率614 W、液料比17.3∶1。在此条件下,莽草酸的平均得率为3.03%。To optimize the microwave-assisted extraction（MAE） of shikimic acid from Illicium verum Hook. f, on the base of single-factor experiment, the extraction time, microwave power and the liquid to solid ratio were studied with the central composite design and their interactions on the yield of shikimic acid were also investigated. The predictive polynomial quadratic equations model was developed by response surface methodology（RSM） software. The optimum extraction condition was obtained as follows： extraction time 19 min, microwave power 614 W and liquid to solid ratio 17.3 ： 1. Under the optimized operating conditions, the extraction rate of shikimic acid is 3.03 %.

关 键 词：莽草酸 八角茴香 微波提取 响应面分析 

分 类 号：O658[理学—分析化学]