前列腺平滑肌肉瘤9例临床病理分析  

Leiomyosarcoma of the prostate:a report of 9 cases

作　　者：文载律[1] 陈乐真[1] 

机构地区：[1]解放军总医院病理科,北京100853

出　　处：《临床与实验病理学杂志》2009年第5期477-480,共4页Chinese Journal of Clinical and Experimental Pathology

摘　　要：目的探讨前列腺平滑肌肉瘤的病理学诊断、组织形态学特征、鉴别诊断及发病率情况。方法收集解放军总医院1990年-2008年19年间共诊出的平滑肌肉瘤9例,做常规HE染色及免疫组化染色,并复习文献。结果前列腺平滑肌肉瘤占同期前列腺恶性肿瘤的1%。患者发病年龄27-56岁,平均43岁。免疫组化染色具有特征,即actin为指标性抗体、其次为calponin,同时muscle、desmin、vimentin亦示阳性反应。结论前列腺平滑肌肉瘤发病率很低,临床上主要以进行性排尿困难。影像学检查有助于发现前列腺占位性病变,确诊要靠前列腺穿刺活检组织学诊断。Purpose To discuss the pathological features,differential diagnosis and the incidence of the prostatic leiomyosarcoma.Methods There were 9 cases of the prostatic leiomyosarcoma from 1990 to 2008 in general hospital of the PLA and were observed by light microscopy,immunohistochemical technique and review of literature.Results The prostatic leiomyosarcoma was accounted for 1% of all the prostatic malignant tumors.The average age was 43 years old,ranged from 27 to 56 years.There were special features of the immunohistochemical staining in the leiomyosarcoma.Conclusions The prostatic leiomyosarcoma is rare and dysuria always the first symptoms.Ultrosound,CT and MRI examinations are helpful to find this tumor.Needle biopsy contributes to a definite diagnosis and the immunohistochemical staining helps to distinguish the disease from other spindle leisions.

关 键 词：前列腺肿瘤 平滑肌肉瘤 免疫组织化学 

分 类 号：R737.25[医药卫生—肿瘤]