阑尾广基锯齿状腺瘤2例临床病理分析  

Appendix Sessile serrated adenoma:a clinicopathologic study of 2 cases

作　　者：石峰[1] 昌红[1] 王莉[1] 高颖[1] 沈兵[1] 齐然[1] 陈奕至[1] 

机构地区：[1]北京世纪坛医院病理科,北京100038

出　　处：《临床与实验病理学杂志》2009年第5期489-490,共2页Chinese Journal of Clinical and Experimental Pathology

摘　　要：目的观察阑尾广基锯齿状腺瘤（SSA）的临床病理形态,对其发生与诊断标准进行探讨。方法对2例阑尾广基锯齿状腺瘤引起的临床表现、术中所见及其病理形态学表现进行观察及分析。结果2例患者均为老年男性患者。病理显示阑尾腺体呈明显锯齿状结构;隐窝不规则;细胞有异型性并可见核分裂（7-10个/10 HPF）;隐窝内黏液增多。病理诊断为＂慢性阑尾炎并SSA＂及＂急性蜂窝织性阑尾炎伴SSA＂。结论阑尾SSA非常罕见,SSA为癌前病变,需与增生性息肉、锯齿状腺瘤等进行鉴别。Purpose To observe the clinical and pathological features of appendix sessile serrated adenoma and study it′s happening process and diagnositic criterion.Methods Observe and study the clinical features,operational findings and pathological findings.Result Two patients are all old male people.Pathology shows the glands have markedly serration,irregular crypt,cell heteromorphism and mitosis（710/10 HPF）,more crypto-mucus.Pathology diagnosis are ＂chronic appendicitis with SSA＂ and ＂acute gangrenous appendicitis with SSA＂.Conclusions Appendix SSA is very rare.SSA is a precancerous change,and it needs to make differenced diagnosis with hyperplastic polyp and serrated adenoma.

关 键 词：阑尾肿瘤 广基锯齿状腺瘤 增生性息肉 锯齿状腺瘤 

分 类 号：R735.36[医药卫生—肿瘤]