28例内窥镜下诊断早期食管癌三维适形放疗的临床观察  

Clinical observation of three dimensional conformal radiotherapy in 28 patients with early esophageal carcinoma diagnosed by endoscopy

作　　者：薛春泉[1] 

机构地区：[1]镇江市第一人民医院放疗科,江苏镇江212002

出　　处：《临床肿瘤学杂志》2009年第10期939-940,共2页Chinese Clinical Oncology

摘　　要：目的:回顾性分析内窥镜下诊断早期食管癌的三维适形放疗的疗效及安全性。方法:28例早期食管癌经内窥镜及碘染色诊断,并经活检组织病理学检查证实,行三维适形放疗。放疗剂量为95%PTV150Gy/25f,5周完成;95%PTV210Gy/5f,1周完成。结果:28例早期食管癌行三维适形放疗,1、3和5年生存率分别为96.4%、78.6%和71.4%。主要的毒副反应为放射性食管炎。结论:早期食管癌行三维适形放疗是有效的方法,照射野大小应根据内窥镜及碘染色所确定的病变范围而定。Objective：To analyze retrospectively efficacy of three dimensional conformal radiotherapy（3DCRT） for early esophageal carcinoma diagnosed by endoscopy.Methods：From March 2003 to October 2007,three dimensional conformal radiotherapy（3DCRT） was used for 28 patients with early esophageal carcinoma diagnosed by endoscopy using Lugol＇s solution and proved by histopathology.3DCRT was 2.0Gy/f,5 fractions a week,to 50 Gy for 95% of PTV1/25f/5w,followed by 10 Gy for 95% of PTV2/5f/1w.Results：Twenty-eight patients with early esophageal carcinoma treated by 3DCRT,The overall 1-,3-and 5-year survival rates were 96.4%,78.6%,71.4%.The major treatment-related toxicity was radiation esophagitis.Conclusion：Three dimensional conformal radiotherapy（3DCRT）is effective in the treatment of early esophageal carcinoma.The length of irradiation field should be decided by endoscopic diagnosis using Lugol＇s solution.

关 键 词：食管肿瘤/三维适形放疗 内窥镜检查 预后 

分 类 号：R730.55[医药卫生—肿瘤] R735.1[医药卫生—临床医学]