平行板流动小室在肿瘤研究中的应用  

Application of parallel-plate flow chamber in cancer research

作　　者：赵莲[1] 廖福龙[2] 韩东[2] 周虹[1] 

机构地区：[1]军事医学科学院野战输血研究所,北京100850 [2]国家纳米科学中心,北京100190

出　　处：《军事医学科学院院刊》2009年第5期482-485,共4页Bulletin of the Academy of Military Medical Sciences

基　　金：国家自然科学基金青年科学基金项目(30800214);国家"973"课题(2009CB521700-02)

摘　　要：平行板流动小室是细胞力学体外实验中最常用的装置之一,越来越多的研究利用平行板流动小室提供剪应力,模拟肿瘤细胞生长的体内环境,探讨肿瘤细胞增殖、黏附和扩散的机制;亦有研究在平行板流动小室的基础上建立了肿瘤检测装置,开辟了生物力学与肿瘤学有机结合的新领域。本文综述了平行板流动小室在肿瘤研究中的应用现状。Parallel-plate flow chamber is a widely used equipment in studying cellular mechanics in vitro. Many researchers used parallel-plate flow chamber to provide shear stress and to mimic in vivo the environment of cancer cell growth. It is a versatile tool in understanding the mechnisms of proliferation, adhesion, and metastasis of cancer cell. Cancer-detecting devices were also developed based on parallel-plate flow chamber. A new field overlapping biomechanics and cancer research was developed. Application of parallel-plate flow chamber in cancer research is reviewed in this paper.

关 键 词：平行板流动小室 肿瘤 肿瘤转移 检测 

分 类 号：R73-3[医药卫生—肿瘤]