前视觉通路病变患者双侧视放射的DTI研究  

The effect of anterior optic pathway lesion on the structure of bilateral optic radiation:a DTI study

作　　者：宋修峰[1] 陈英敏[2] 朱月莉[1] 张通[1] 

机构地区：[1]山东省青岛市市立医院影像科,山东青岛266002 [2]河北省人民医院,河北石家庄050051

出　　处：《医学影像学杂志》2009年第11期1366-1368,共3页Journal of Medical Imaging

摘　　要：目的:应用DTI研究双侧视放射白质纤维束的异常,探讨前视路病变对双侧视放射结构的影响。方法:青光眼、垂体瘤及正常对照组各16例行DTI检查。分别测量双侧视放射的FA均值。对测量结果,应用SPSS13.0两样本-t检验统计分别分析患者组双侧视放射FA值并与正常对照组比较。结果:青光眼组及垂体瘤组左、右侧视放射FA值均比正常对照组显著下降。结论:前视路受损患者双侧视放射的白质纤维束受到损害,为进一步了解其神经病理学机制及评估预后提供新的思路。Objeclive：The DTI was employed to explore the structure abnormality of the bilateral optic radiation in patient with anterior optic pathway lesion. Methods： 16 glaucoma, 16 pituitary macroadenoma, and 16 normal subjects received DTI. Two-sample t-tests was used to evaluate the difference of the FA value between the patients and normal controls. Results： The FA value in the bilateral optic radi- ation was obviously decreased in the glaucoma/pituitary adenoma patients than in the normal controls. Conclusion： The bilateral optic radiation is damaged in patient with anterior optic pathway lesion, which can help understand the neuropathological mechanism and evaluate the prognosis.

关 键 词：磁共振成像 弥散张量成像 前视觉通路 青光眼 垂体瘤 

分 类 号：R775.1[医药卫生—眼科] R445.2[医药卫生—临床医学]