婴儿气质与脐血单胺类神经递质关系的研究  

Study on relationship between infant temperament and the level of monoamine neurotransmitters in cord blood

作　　者：岳阳[1] 黄春香[1] 马静[1] 皮丕湘[2] 

机构地区：[1]中南大学湘雅二医院精神卫生研究所,长沙410011 [2]中南大学湘雅二医院产科

出　　处：《国际精神病学杂志》2009年第4期200-202,共3页Journal Of International Psychiatry

基　　金：国家自然科学基金项目资助(项目号:30470620)

摘　　要：目的探讨婴儿气质与脐血5-羟色胺(5-HT)、去甲肾上腺素(NE)、肾上腺素(E)及多巴胺(DA)水平的关系。方法采集76例健康新生儿脐带血检测5-HT、NE、E和DA的血浆浓度,于婴儿1～4个月时采用小婴儿气质问卷(EITQ)评估其气质特征。结果(1)脐血中DA、NE、E的水平无性别差异,5-HT的水平女性高于男性,有显著性差异(P<0.05);(2)5-HT水平影响婴儿的适应性与注意力分散度,E水平影响其适应性,而DA、NE与婴儿气质特征无关联。结论女性脐血5-HT水平高于男性;5-HT、E的水平较高其婴儿适应性较低,而5-HT水平高,注意力更不容易分散。Objective To study whether monoamine neurotransmitters in neonate＇s cord blood is related to infant temperament. Methods Seventy-six healthy babies were randomly chosen in Changsha and their cord blood was drown when they were born. The levels of blood 5 - HT, NE （ norepinephrine）, E （epinephrine） and DA （ do- pamine） were determined. They were assessed after 1 - 4 months by Early Infancy Temperament Questionnaire （EI- TQ） . Results （ 1 ） The level of 5 - HT was significantly higher in females than in males in neonate＇ s cord blood, the levels of NE, E and DA were no significant sex differences; （2） 5 - HT levels affect infant＇ s adaptability and at- tention dispersity, E levels affect adaptability too. The levels of E and DA were not correlated with temperament traits. Conclusions The level of 5 - HT in neonate＇ s cord blood of female is higher than that in male. The higher the 5 - HT and E levels are related with the lower infants＇ adaptability, while the attention of infant with higher the 5 -HT levels is harder to be dispersed.

关 键 词：婴儿 气质 单胺类神经递质 

分 类 号：R749[医药卫生—神经病学与精神病学]