准分子激光角膜切削术后的屈光回退  

Myopic regression after photorefractive keratectomy

作　　者：庞国祥[1] 詹素华[1] 李莹[1] 金玉梅[1] 孙玉敏[1] 李维业[1] 

机构地区：[1]中国医学科学院中国协和医科大学北京协和医院眼科

出　　处：《中华眼科杂志》1998年第6期451-453,共3页Chinese Journal of Ophthalmology

摘　　要：目的通过准分子激光角膜切削术（ｐｈｏｔｏｒｅｆｒａｃｔｉｖｅｋｅｒａｔｅｃｔｏｍｙ，ＰＲＫ）术后屈光回退的分析，以期探讨可能影响回退的因素。方法经ＰＲＫ手术治疗近视于术后发生回退（≥－１．００Ｄ）１０３只眼，术前屈光度－４．００～－１４．５０Ｄ（－８．７５±２．６５Ｄ）。分为二组进行比较，Ⅰ组为中度近视（－４．００～－７．９０Ｄ），Ⅱ组为高度近视（≥－８．００Ｄ）。结果中度近视回退率１．１７％，高度近视回退率６．９３％（Ｐ＜０．００１）。高年龄组回退率较低年龄组高（Ｐ＜０．０１）。较严重的角膜上皮下雾状混浊（ｈａｚｅ）多与回退伴行。因激素性高眼压减少或停止局部糖皮质激素的应用可导致回退，屈光的稳定性与性别无关，回退常伴Ｋ值增大。结论回退与预期矫正度。Objective To investigate myopic regression after excimer laser photorefractive keratectomy (PRK) in patients with myopia. Methods 103 eyes with regression (≥-1.00 D) found in the follow up for more than 1 year were included in this study. The preoperative spherical equivalent was -4.00～-14.50 D (-8.72± 2.65 D). Patients were divided into two groups: (1) moderate myopia (-4.00～-7.90 D) and (2) high myopia (≥-8.00 D). Results A significant positive correlation was found between regression and the extent of attempted correction, the rate of regression in high myopia group was 6.93% and that in moderate group, 1.17%. The rate of regression in older age group was higher than that in younger cases. ( P <0.01). Relatively severe haze under the corneal epithelium often accompanies the regression, and decrease of the dosage of topical corticosteroid application or its withdrawal because of the development of corticosteroid ocular hypertention could lead to the regression. The stability of the refraction is not related to the difference in sex. The regression is often accompanied by the increase in K value. Conclusion The regression is significantly related to the extent of attempted correction, patients′ age, corneal haze and topical application of corticosteroid.

关 键 词：近视 角膜切削术 RRK 屈光回退 

分 类 号：R778.110.5[医药卫生—眼科] R779.63[医药卫生—临床医学]