脑肿瘤伽玛刀治疗后磁共振波谱评价  

Evaluation on the value of treated brain tumors with proton MR spectroscopy

作　　者：任远[1] 李明智[1] 王川红[1] 

机构地区：[1]江西省人民医院,南昌330006

出　　处：《江西医药》2009年第10期953-954,共2页Jiangxi Medical Journal

基　　金：江西省卫生厅课题:课题编号20063018

摘　　要：目的评估脑肿瘤伽玛刀治疗后的1H-MRS的临床应用价值。方法对30例脑肿瘤伽玛刀治疗前、后行单体素1H-MRS检查。结果脑肿瘤伽玛刀治疗后肿瘤生长抑制,1H-MRS表现为NAA\Cr、Cho\Cr、Cho\NAA比值下降,其中Cho\Cr、Cho\NAA比值下降明显。放射性坏死1H-MRS表现为肿瘤坏死区Cho、NAA、Cr峰消失,出现乳酸-脂质峰。肿瘤未复发患者1H-MRS未见明显异常;肿瘤复发患者1H-MRS表现为Cho、Cho/NAA峰再升高,出现乳酸峰。结论1H-MRS有助于鉴别脑肿瘤行伽玛刀治疗后复发与坏死;评估脑肿瘤行伽玛刀治疗后的代谢变化,是一种判断伽玛刀疗效的有价值的辅助检查方法。Objective To evaluate the clinical application of proton MR spectroscopy in patients with treated brain tumors. Methods Thirty patients with treated brain tumors underwent proton MR spectroscopy.Results Tumor inhibited by radiation had decreased Cho, NAA and Cr on proton MRS. Tumor radiation necrosis showed high Lac-Lip peak on proton MRS.Conclusion The proton MR spectroscopy was a valuable methods in evaluation of treated tumors and could detect the recurrent brain tumors after operation and pathologic changes of the tumors after radiotherapy.

关 键 词：脑肿瘤 磁共振波谱学 代谢 放射治疗 

分 类 号：R739.41[医药卫生—肿瘤]