新鲜羊膜移植治疗巨大翼状胬肉的临床观察  

Clinical Observation of Extended Removal of Large Pterygium Followed by Fresh Amniotic Membrane Transplantation

作　　者：刘凤阁[1] 郭向欣[1] 石义明 孔祥峰[1] 李颖[1] 银哲 

机构地区：[1]山东省邹城市人民医院眼科,273500

出　　处：《中华全科医学》2009年第12期1325-1327,共3页Chinese Journal of General Practice

摘　　要：目的观察大范围胬肉切除联合新鲜羊膜移植术在治疗巨大翼状胬肉的临床疗效。方法显微镜下行大范围翼状胬肉切除联合新鲜羊膜移植术63例(67眼),观察术后胬肉复发及眼表修复情况。结果术后早期均有不同程度的结膜及植片充血、水肿和异物感,未见明显排斥反应发生,无感染。6周左右羊膜吸收,血管化完成,透明、光滑、稍显苍白,难与自身结膜区分开正常的,美容效果好。羊膜植片成活63眼,4眼植片溶解滑落。术后随访观察10～30个月,5眼复发,62眼治愈,复发率为7.4%。结论大范围翼状胬肉切除联合新鲜羊膜移植治疗巨大翼状胬肉能良好促进眼表的修复,有效降低胬肉的复发,手术安全性高;且新鲜羊膜取材方便,手术操作简单,有利于基层医院开展。Objective To observe the effect of extended removal of large pterygium followed by fresh amniotic membrane transplantation.Methods By microscope,extended removal of large pterygium followed by amniotic membrane transplantation was performed in 63 cases（67 eyes）.The situation of pterygium recurrence and ocular surface repair after surgery were observed.Results Different degree conjunctiva and transplantation patch engorgement、edema and eyewinker affection were observed in all patients after surgery forepart.No acute rejection and infection were observed.About 6 weeks amniotic membrane was absorbed and blood vessel upgrowth was accomplished.Amniotic membrane was transparency,lubricity and paleness.It was difficult to distinguish from natural conjunctiva,the effect of outward appearance was fine.63 eyes of amniotic membrane transplantation patchs survived,4 eyes were dissolved.After postoperative 10-30 months follow-up,5 eyes recurced,62 eyes were cured,the recurrence rate was 7.4%.Conclusion The extended removal of large pterygium followed by amniotic membrane transplantation can effectively reduce the recurrence of pterygium.The operation was safe and simple,and it can be carried out in fundmental hospital.

关 键 词：巨大翼状胬肉 新鲜羊膜 移植 

分 类 号：R772.2[医药卫生—眼科]