STAT信号通路与黑色素瘤  

Relationship between STAT signal pathway and melanoma

作　　者：唐琼玲[1] 朱月春[1] 

机构地区：[1]昆明医学院生化教研室,昆明650031

出　　处：《生命的化学》2009年第6期799-802,共4页Chemistry of Life

基　　金：国家自然科学基金(30460049;30860322);云南省人才科研基金(2007PY01-13)资助

摘　　要：信号转导和转录激活因子(signal transducers and activators of transcription,STAT)的家族成员STAT1、STAT3、STAT5与黑色素瘤的发生发展密切相关。本文就STAT1、STAT3、STAT5与黑色素瘤的发生、转移以及治疗等的关系的研究进展作一概述。STAT1, STAT3, and STAT5, which are members of signal transducers and activators of transcription family, have very close correlation with the genesis and development of human melanoma. This paper summarized the roles of the STAT1, STAT3 and STAT5 signaling pathways in the genesis, development, invasion, metastasis and therapy of melanoma, which provides some new ideas for improving melanoma therapeutic effect.

关 键 词：STAT 信号转导 黑色素瘤 

分 类 号：R739.5[医药卫生—肿瘤]