血清a-L-岩藻糖苷酶检测在肝脏疾病中的应用  

Determination of α- L - Fucosidase Activity in Liver Disease and Its Application

作　　者：王玉兰[1] 谷静丽[1] 刘彬[1] 康玉华[2] 

机构地区：[1]开封医专生物化学教研室 [2]开封医专附属淮河医院内二

出　　处：《开封医专学报》1998年第2期7-9,共3页Journal of Henan University(Medical Science)

摘　　要：检测原发性肝癌(PHC)、肝硬化、转移性肝癌,其它肝脏疾病及健康人血清α-L-岩藻糖苷酶(αFu)活力.结果表明:PHC组αFu活性显著高于其它肝病各组(P<0.01),与正常对照组相比较有极显著差异(P<0.001).提示αFu中作为PHC诊断的辅助性指标.αFu与αFP联合检测可使PHC诊断的阳性率提高至93.0%.The activity of serum α - L - fucosidase was determined in patients with primary hepatic carcinoma (PHC), other liver disease extrahepatic rumers and 100 normal control subjects. The result show a significant elevation of enzyme activity in PHC compareed with other groups ( P < 0. 01) except metastatic hepatic carcinoma. α- L- fucosidas activity is a useful parameter for auxiliary diagnosis of PHC. Determination α - L - fucosidas activity with AFP could promote the diagnostic accuracy of PHC.

关 键 词：岩藻糖苷酶 肝脏疾病 原发性 肝癌 转移性 

分 类 号：R735.704[医药卫生—肿瘤] R446.112[医药卫生—临床医学]