口服大蒜素引起急性多形性红斑  

Acute multiform erythema induced by oral allitrid

作　　者：王新[1] 邹建明[1] 吴苏宁[1] 

机构地区：[1]无锡市第三人民医院口腔科,江苏无锡214041

出　　处：《药物不良反应杂志》2009年第5期366-366,共1页Adverse Drug Reactions Journal

摘　　要：1例25岁女性患者因霉菌性阴道炎口服大蒜素20mg。2h后,患者双上肢出现散在红斑,随后扩散至全身;红斑呈对称性、鲜红色,部分表面有渗出;病变部位灼热、瘙痒;面部水肿,口腔黏膜及上唇糜烂,尿道口及阴道口轻度水肿、充血并伴有关节酸痛。T39.0℃。立即静脉滴注地塞米松及维生素C,同时给予甲泼尼龙口服,局部外用药物治疗。10d后红斑消退。A 25-year-old woman with colpitis mycotica received oral allitrid 20 mg. Two hours later,the patient developed sporadic erythema in her upper limbs which progressed to involve her entire body. The erythma was symmetry and rednees with exduation at some sites. Her lesion site was calor and itching. Meanwhile she experienced facial edema,erosion of oral mucosa and upper lip,slight edema and hyperemia of urethral meatus and vaginal orifice,as well as arthralgia. Her temperature was 39.0℃. An IV infusion of dexamethasone and vitamin C were given immediately. Meanwhile she treated with oral methylprednisolone and drug for external application. Ten days later, her erythema gradually subsided.

关 键 词：大蒜素 不良反应 急性多形红斑 

分 类 号：R758.2[医药卫生—皮肤病学与性病学]