穿心莲内酯提取工艺研究  

Study of Andrographolide's Extraction

作　　者：吴爱群[1] 张国强[1] 

机构地区：[1]河池学院化学与生命科学系,广西宜州546300

出　　处：《河池学院学报》2009年第5期66-68,共3页Journal of Hechi University

基　　金：广西自然科学基金资助项目(桂科自0899025);河池学院科研基金资助项目(2006A-N003)

摘　　要：采用正交实验法探讨穿心连内酯的提取工艺,以提取的内酯量为参考指标,考察了料液比、乙醇浓度、提取温度和提取时间等影响因素。确定影响穿心莲内酯提取率的因素大小顺序为:乙醇浓度>提取温度>料液比>提取时间,其最佳工艺条件为:60℃下,用1500mL75%的乙醇对100g穿心莲进行浸提2h,得622mg穿心莲内酯。Extraction process of andrographolide is studied by the orthogoanal experimental design. As the evaluate target about the content of andrographolide＇ s extraction, we study the effective factors about rate of material and solvent, alcohol concentration, temperature and time. The results showed that alcohol concentration the most effective factor, temperature the second, rate of material and solvent the third, the last was time. The optimal condition is got as follows： the extraction amount is 622 mg when we immerse the 100 g Andrographis Panicuha into 75% alcohol for 2 hours at 60℃.

关 键 词：穿心莲 穿心莲内酯 提取 

分 类 号：R931.7[医药卫生—生药学]