十二指肠球部胃黏膜异位的内镜与病理探讨  

作　　者：章亚娣[1,2] 潘文胜[1] 沈虹[3] 王海军[4] 许晶虹[4] 张顽军[1] 武良琴[1] 徐翔[5] 

机构地区：[1]浙江大学医学院附属第二医院消化内科,310009 [2]杭州市小营社区卫生服务中心 [3]浙江大学医学院附属第二医院肿瘤内科 [4]浙江大学医学院附属第二医院病理科 [5]浙江大学医学院附属第二医院药剂科

出　　处：《当代医学》2009年第36期1-3,共3页Contemporary Medicine

基　　金：公益性行业科研专项经费支持(200802112);浙江省卫生厅资助项目(2007A093;2008A094);中医药管理局资助项目(2007ZA019);浙江省自然科学基金资助项目(Y208001)

摘　　要：目的探讨十二指肠球部胃黏膜异位的内镜下表现、分型和病理特征。方法收集浙江大学附属第二医院2004年1月～2009年10月经内镜和病理检查确诊为十二指肠球部胃黏膜异位的27例病人进行内镜下分型并观察其病理特征。结果(1)根据内镜下表现可分为3型,结节型13例(12例为单发小结节,1例为单个大结节);平坦隆起型9例;颗粒型5例。(2)27例病人中26例异位的胃黏膜上Hp(幽门螺旋杆菌)阴性,1例为阳性。(3)27例病人均伴有慢性胃炎,6例伴有十二指肠球部炎。(4)27例病人的内镜和病理学检查有3例合并十二指肠球部溃疡,27例均无癌变。结论十二指肠球部胃黏膜异位在内镜下肉眼观察可分为3型,其中结节型最为常见,异位的胃黏膜多不合并HP感染,但会发生十二指肠球部溃疡,一般不会发生癌变。Objective To investigate the clinicalpathological features of ectopic gastric mucosa in the duodenal bulb （HGMDB）. Methods The endoscopic and pathologic features of 27 cases of HGMDB were studied. Results （1）HGMDB can be divided into three types：13 cases of nodular type; 9 cases of flat elevated type; 5 cases of scattered particles. （2）Helicobacter Pyloli （Hp） was negative in 26 cases, positive in 1 case. （3）27 cases were accompanied with chronic gastritis, and 6 case were accompariied with duodenal inflammation. （4）3 cases in 27 cases suffered from duodenal ulcer. There were no cancer in the whole 27 patients. Conclusion HGMDB can be divided into three types, of which the most common type was nodular type, ectopic gastric mucosa were not usually accompanied with HP infection. But it will happen with duodenal ulcer. But it should be further studied whether cancer may occur in the ectopic gastric mucosa.

关 键 词：十二指肠 胃黏膜 异位 内镜 病理 分型 

分 类 号：R574[医药卫生—消化系统]