减瘤手术在晚期肺癌治疗中的应用研究  

Cytoreductive surgery in the treatment of advanced lung cancer research

作　　者：祝宇飞[1] 

机构地区：[1]河南省商丘市第一人民医院,476100

出　　处：《中国医学创新》2009年第35期10-11,共2页Medical Innovation of China

摘　　要：目的初步探讨减瘤手术在晚期肺癌治疗方面的实用价值。方法选择2006年1月至2008年1月笔者所在医院收治的的中晚期肺癌患者20例，采用减瘤手术治疗。选择同时期15例剖胸探查肺肿物活检患者作为对照组。研究分析两组患者术后生存质量及生存时间的差异。结果减瘤组患者生存质量较好率为40．0％，对照组为20．0％，两组间比较差异有统计学意义（χ^2=7．21，P〈0．05）。生存质量评分减瘤组为（35．3±8．2）分，对照组为（27．9±7．1）分，两组间比较差异有统计学意义（t=6．59，P〈0．05）。平均生存时间减瘤组患者为11．6个月，对照组为10．3个月，两组间比较，差异无统计学意义（t=2．41，P〉0．05）。结论减瘤手术可改善中晚期或已有远处转移的肺癌患者的生存质量。Objective To investigate the practical value of cytoreductive surgery in the treatment of advanced lung cancer. Methods Twenty patients with advanced lung cancer were treated by cytoreductive surgery, admitted to our hospital from January 2006 to January 2008 years. To select 15 cases of exploratory thoracotomy in patients with lung tumor biopsy in patients as a control group in the same period. To analyze postoperative quality of life and survival of the time difference be- tween patients in two groups. Results The better quality of life rate of tumor patients in cytoreductive surgery group was 40. 0%, while it was 20. 0% in the control group, and the difference between the two groups was significant （χ^2 = 7.21, P 〈 0. 05 ）. Quality of life score in cytoreductive tumor group was （ 35.3 ± 8.2 ） points, and the score in the control group was （27.9 ± 7. 1 ） points, and the difference between the two groups was statistically significant （ t = 6. 59, P 〈 0. 05 ）. The average survival time by tumor patients was 11.6 months,while in the control group it was 10. 3 months. There was no statistically significant difference （ t = 2.41, P 〉 0. 05 ） between the two groups. Conclusion Cytoreductive surgery may improve the quality of life of patients with the advanced lung cancer.

关 键 词：减瘤手术 肺癌 手术治疗 

分 类 号：R734.2[医药卫生—肿瘤] R289.5[医药卫生—临床医学]