液基细胞学检测蒙汉族妇女宫颈病变的临床分析  

Clinical Analysis of Cervical Smear Using Thinprep Cytologic Test in Mongolian Women and Han Women

作　　者：包秀芳[1] 孙萍[1] 马广清[1] 金莲[1] 武宏丽[1] 

机构地区：[1]内蒙古民族大学附属医院妇产科,内蒙古通辽028000

出　　处：《内蒙古医学杂志》2009年第10期1156-1158,共3页Inner Mongolia Medical Journal

基　　金：内蒙古民族大学2008年度校级科研项目(批准号:mdx2008082)

摘　　要：目的：分析内蒙古通辽地区蒙汉族女性宫颈病变发生率和临床特征,为蒙古族妇女子宫颈癌的预防提供相关信息。方法：应用液基细胞学检查方法,分别选择2008年1月-2009年6月在我院就诊的3 085例蒙古族妇女（A组）和5 811例汉族妇女（B组）的宫颈脱落细胞进行宫颈病变筛查,依据目前国际通用的Bethesda系统（TBS）分类标准进行诊断,对筛查结果为宫颈上皮细胞异常病例进行统计学分析比较。结果：①宫颈上皮细胞异常的总发生率A组为14.17%（437/3 085）、B组为13.03%（757/5 811）,差异无统计学意义（P〉0.05）;②宫颈上皮细胞异常发生情况,不典型鳞状细胞（atypical squamous cell of undetermined signif-icance,ASCUS）、低度鳞状上皮内瘤变（low grade squamous intraepithelial lesion,LSIL）、高度鳞状上皮内瘤变（high grade squamous intraepithelial lesion,HSIL）、鳞癌以及非典型腺细胞的发生率A组分别为12.61%、0.84%、0.36%、0.07 ％、0．29％，组间比较差异无统计学意义（P〉0．05）；③A组60～69岁组宫颈上皮细胞异常的发生率最高（28．57％），而B组为20～29岁组的发生率最高（15．98％）。结论：内蒙古通辽地区蒙汉族女性宫颈上皮细胞病变发生率相比差异无统计学意义。蒙古族女性宫颈病变患病年龄较汉族女性的患病年龄偏高，液基细胞学检查在我区对提高宫颈癌筛查效率及覆盖率是一种切实、可行的方法。Objective： To analyze the incidence and clinical characteristics of cervical diseases in mongolian women and han women in tongliao city of inner mongolia, for providing related data for preventing from cervical cancers in mongolian women. Methods：3 085 mongolian women（group A） and 5 811 han women （group B） in our hospital had been examined by thinprep cytologic test（TCT） and TBS diagnostic system from January 2008 to June 2009. The abnormal cases which had been selected by TCT were statistically analyzed and compare＆ Results： （1）The total incidence of abnormal cervical epithelial patterns in group A and B was respectively 14.17 % （437/3 085）and 13.03 % （757/5 811） （P 〉0.05） ; （2）The conditions of abnormal cervical epithelial patterns, the incidence of cervical atypical squamous cell of undetermined significance（ASCUS）low grade squamous intraepithelial lesion（LSIL）, high grade squamous intraepithelial lesion（HSIL）, squameous cancer and atypical adenomous cells in group A was respectively 12.61%, 0.84 %, 0.36 %, 0.07 % , 0.29 %, which was respectively 11.22 %, 0.88 %, 0.57 %, 0.07 % , 0.29 % in group B, the differences showed no statistically significances（ P 〉0.05） ; （3）The incidence of abnormal cervical epithelial patterns in group A was highest（28.57 % ） in cases in age between 60--69 years old, but it in group B was highest （15.98%）in cases in age between 20--29 years old. Conclusion： There is no difference in the cervical intraepithelial lesions between mongolian and ban women, but the age of mongolian cases is older than han cases. TCT smear screening is necessary, safe and feasible for routine tests in improving efficacy and coverage rate of screening cervical cancer in our region.

关 键 词：宫颈涂片 液基超薄细胞技术 TBS系统 

分 类 号：R737.33[医药卫生—肿瘤]