磁共振技术评价头颈部肿瘤放疗后涎腺功能的应用及进展  

Advance in MR imaging for evaluation of postradiotherapy salivary function in patients with head and neck cancer

作　　者：欧丹(综述)[1] 何霞云(审校)[1] 

机构地区：[1]复旦大学附属肿瘤医院放疗科,复旦大学上海医学院肿瘤学系,上海200032

出　　处：《中国癌症杂志》2009年第11期875-880,共6页China Oncology

摘　　要：口干是头颈部肿瘤放疗后最常见且最突出的晚期反应之一,当前各种检测涎腺功能的手段都有一定的不足。磁共振涎管成像(magnetic resonance sialography,MRS)和扩散加权磁共振成像(diffusion-weighted magnetic resonance imaging,DW MRI)是近年新发展起来的涎腺功能评价方法,具有无创、无辐射的特点。本文就该技术在涎腺功能评价方面的应用进展作一综述,为探讨头颈部肿瘤患者放疗前后涎腺功能变化监测手段的发展方向提供参考。Salivary gland damage with subsequent xerostomia has been an unavoidable complication in most head and neck cancer patients after radiotherapy. However, there were many shortcomings of each current detecting technique. Magnetic resonance sialography （MRS） and diffusion-weighted magnetic resonance imaging （DW MRI）, as two of the most important progresses in the latest MRI techniques, with the virtue of non-invasion and non-ionizing radiation, has been rapidly developed in salivary function assessment in recent years, and it has kept on improving technically. This article mainly reviewed the clinical applications and research advances of these two MRI technologies in post-radiotherapy salivary function assessment in patients with head and neck cancers, so as to provide reference for further study.

关 键 词：磁共振涎管成像 扩散加权磁共振成像 口腔干燥 放疗后涎腺功能 

分 类 号：R730.42[医药卫生—肿瘤] R739.91[医药卫生—临床医学]